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了解临床试验结果测量的可靠性:以手术或血管内治疗动脉瘤的血管造影结果为例。

Understanding the reliability of trial outcome measures: The example of angiographic results of surgical or endovascular treatments of aneurysms.

机构信息

Department of Radiology, service of Neuroradiology, Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada.

Department of Radiology, service of Neuroradiology, Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada.

出版信息

Neurochirurgie. 2022 Oct;68(5):485-487. doi: 10.1016/j.neuchi.2022.04.004. Epub 2022 May 31.

Abstract

BACKGROUND

The reliability of outcome measures is of central importance in clinical research. Studies of reliability remain rare in the neurovascular field.

METHODS

A narrative review of the history (1997-2021) of reporting angiographic results of the surgical or endovascular treatments of aneurysms serves to illustrate the importance of precisely defining outcome measures. We also review how the reliability of an angiographic classification system was studied.

DISCUSSION

Outcome measures are commonly used without precise definitions. When definitions or classification systems exist, they are rarely verified for their reliability. Twenty-five years following its introduction, a classification of angiographic results of aneurysm treatments is still being studied and modified.

CONCLUSION

The reliability of outcome measures should be made a research priority if we are to practice outcome-based medical or surgical care.

摘要

背景

在临床研究中,结果测量的可靠性至关重要。神经血管领域的可靠性研究仍然很少。

方法

对 1997 年至 2021 年期间手术或血管内治疗动脉瘤的血管造影结果报告的历史进行叙述性回顾,以说明精确定义结果测量的重要性。我们还回顾了如何研究血管造影分类系统的可靠性。

讨论

结果测量通常在没有精确定义的情况下使用。当存在定义或分类系统时,很少对其可靠性进行验证。在其引入 25 年后,一种对动脉瘤治疗血管造影结果的分类仍在研究和修改中。

结论

如果我们要实践基于结果的医疗或手术护理,就应该将结果测量的可靠性作为研究重点。

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