Yang Guangmin, Ge Hongwei, Wu Guangyan, Zhang Yepeng, Zhang Leiyang, Zhang Ming, Li Xiaoqiang, Zhou Min
Department of Vascular Surgery, Drum Tower Hospital, Affiliated to School of Medicine, Nanjing University, Nanjing, China.
Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Front Cardiovasc Med. 2022 May 17;9:847368. doi: 10.3389/fcvm.2022.847368. eCollection 2022.
This study was performed to compare aortic remodeling and clinical outcomes in patients with acute, subacute, and chronic type B aortic dissection (TBAD) after thoracic endovascular aortic repair (TEVAR).
We retrospectively examined 323 consecutive patients with acute ( = 129), subacute ( = 161), and chronic ( = 33) TBAD who underwent TEVAR from June 2013 to December 2016 in in multicenter institution. Patient demographics, clinical data, and imaging characteristics were recorded and compared among the three groups.
The three groups had comparable baseline characteristics. Perioperative mortality rates were similar among the acute (2.3%), subacute (0.0%), and chronic (0.0%) groups ( = 0.34). Perioperative morbidity rates, including the rates of visceral and lower limb malperfusion and cerebral infraction, were also similar. The rate of perioperative endoleak was significantly higher in the chronic group (18.1%) than in the acute (3.9%) and subacute (3.7%) groups ( = 0.02). The mean follow-up duration was 78 ± 22 months (range, 36-101 months). The mortality rates were comparable among the three groups. The rates of reintervention and lower limb malperfusion were higher in the chronic group than in the acute and subacute groups. FL diameter reduction were more robust in the acute and subacute groups than in the chronic group.
Patients with acute, subacute, and chronic TBAD had different outcomes in this study. Patients with acute and subacute TBAD had fewer complications than those with chronic TBAD. Aortic remodeling after TEVAR was more favorable in patients with acute and subacute TBAD than in patients with chronic TBAD. TEVAR promotes more positive remodeling at the stent graft level than at the distal level of the aorta.
本研究旨在比较胸主动脉腔内修复术(TEVAR)治疗急性、亚急性和慢性B型主动脉夹层(TBAD)患者后的主动脉重塑情况及临床结局。
我们回顾性研究了2013年6月至2016年12月在多中心机构接受TEVAR治疗的323例连续性急性(n = 129)、亚急性(n = 161)和慢性(n = 33)TBAD患者。记录并比较三组患者的人口统计学资料、临床数据和影像学特征。
三组患者的基线特征具有可比性。急性组(2.3%)、亚急性组(0.0%)和慢性组(0.0%)的围手术期死亡率相似(P = 0.34)。围手术期发病率,包括内脏和下肢灌注不良及脑梗死发生率也相似。慢性组围手术期内漏发生率(18.1%)显著高于急性组(3.9%)和亚急性组(3.7%)(P = 0.02)。平均随访时间为78±22个月(范围36 - 101个月)。三组患者的死亡率具有可比性。慢性组再次干预率和下肢灌注不良发生率高于急性组和亚急性组。急性组和亚急性组假腔直径缩小比慢性组更显著。
本研究中急性、亚急性和慢性TBAD患者的结局不同。急性和亚急性TBAD患者的并发症少于慢性TBAD患者。TEVAR术后急性和亚急性TBAD患者的主动脉重塑比慢性TBAD患者更有利。TEVAR在支架移植物水平促进的重塑比在主动脉远端水平更积极。