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奥罗拉水性引流植入物(AADI):适应证、作用机制、手术技术、结果、影响和局限性的综述。

Aurolab Aqueous Drainage Implant (AADI): Review of Indications, Mechanism, Surgical Technique, Outcomes, Impact and Limitations.

机构信息

VST Centre for Glaucoma Care, LV Prasad Eye Institute, Hyderabad, India.

出版信息

Semin Ophthalmol. 2022 Oct-Nov;37(7-8):856-868. doi: 10.1080/08820538.2022.2082254. Epub 2022 Jun 3.

Abstract

PURPOSE

The purpose of this review is to place together all the knowledge available on aurolab aqueous drainage implant (AADI) in one place for the benefit of all glaucoma specialists who are interested in low-cost implants in developing world with desired results.

METHODS

A comprehensive literature search was done on AADI and its use in glaucoma management. 35 results were obtained from the literature search. Out of these 35, 2 were commentaries, 6 were case reports and rest 27 were studies (prospective and retrospective) discussing the surgical outcomes, modifications and comparison of AADI with other glaucoma drainage devices (GDDs). Out of these, 2 commentaries were excluded and rest 33 articles were included, cited and discussed appropriately in this review.

RESULTS

AADI resulted in a significant reduction in the intra ocular pressure (IOP) and also in the number of antiglaucoma medications. AADI can be implanted alone or combined with cataract surgery. It was found to be beneficial in both pediatric and adult refractory glaucoma. There was no significant difference seen in the pre and post operative visual acuity. But AADI was also associated with various hypotony related and tube related early and late onset complications. Some of these complications were managed conservatively and some needed surgical intervention.

CONCLUSIONS

AADI is a low-cost non-valved GDD with successful results in both adult as well as pediatric refractory glaucomas. Early and late onset complications are common and can be managed with appropriate and timely medical or surgical intervention.

摘要

目的

本综述的目的是将有关水凝胶引流植入物(AADI)的所有现有知识汇集在一起,以供所有对发展中国家低成本植入物感兴趣并希望获得理想结果的青光眼专家参考。

方法

对 AADI 及其在青光眼管理中的应用进行了全面的文献检索。从文献检索中获得了 35 个结果。在这 35 个结果中,有 2 个是评论,6 个是病例报告,其余 27 个是研究(前瞻性和回顾性),讨论了 AADI 的手术结果、改良以及与其他青光眼引流装置(GDD)的比较。其中,有 2 个评论被排除在外,其余 33 篇文章被包括在内,并在本综述中进行了适当的引用和讨论。

结果

AADI 可显著降低眼内压(IOP)和抗青光眼药物的使用次数。AADI 可单独植入或与白内障手术联合植入。它已被证明对小儿和成人难治性青光眼均有益。术前和术后视力无明显差异。但是,AADI 也与各种与眼压降低相关以及与引流管相关的早期和晚期并发症有关。这些并发症中的一些可以通过保守治疗来管理,而有些则需要手术干预。

结论

AADI 是一种低成本的非瓣膜 GDD,在成人和儿童难治性青光眼中均取得了成功的结果。早期和晚期并发症很常见,可以通过适当和及时的医疗或手术干预来管理。

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