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雷尔氏菌和尿路感染:在马里的一名 HIV 感染者中首次经实验室确认的病例。

Raoultella planticola and urinary tract infection: The first laboratory-confirmed case in an HIV-infected patient in Mali.

机构信息

Department of Infectious Diseases, Point G Teaching Hospital, Bamako, Mali.

Faculty of Medicine and Dentistry, University of Sciences, Techniques and Technologies of Bamako, Mali.

出版信息

J Infect Dev Ctries. 2022 May 30;16(5):909-912. doi: 10.3855/jidc.15688.

Abstract

Raoultella planticola is a Gram-negative, aerobic, non-motile bacterium, abundant in the environment, but rarely associated with pathology in humans. Notably, few urinary tract infections caused by R. planticola have been reported. To our knowledge, we are presenting here the first case of urinary tract infection caused by R. planticola in an HIV-infected individual. It is a 50-year-old female, with a history of HIV-1 infection treated for three years. At admission, her CD4 count was 70 cells/mL, and the main complaints were severe diarrhea and cough. She was diagnosed and treated for pulmonary tuberculosis (TB) and E. Coli enteritis. Initially, we observed a good evolution. However, on day 21 of hospitalization, she presented with fever and dysuria. Urinalysis revealed the presence of R. planticola with resistance to multiple antibiotics. We also detected that she has an HIV-2 but not HIV-1 infection. After receiving the right regimen, she was confirmed cured of her bacterial infections.

摘要

产碱杆菌是一种革兰氏阴性、需氧、非运动的细菌,在环境中大量存在,但很少与人类疾病有关。值得注意的是,由产碱杆菌引起的尿路感染病例很少报道。据我们所知,我们在此报告首例 HIV 感染者产碱杆菌尿路感染病例。该患者为 50 岁女性,HIV-1 感染病史 3 年,入院时 CD4 计数为 70 个/毫升,主要症状为严重腹泻和咳嗽。她被诊断为肺结核(TB)和大肠埃希菌肠炎,并接受了相应治疗。起初,病情有所好转。然而,入院第 21 天,她出现发热和尿痛。尿液分析显示存在产碱杆菌,且对多种抗生素有耐药性。我们还发现她感染了 HIV-2,而非 HIV-1。在接受正确的治疗方案后,她的细菌感染得到了确认治愈。

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