Multivariate Models of Blood Glucose Prediction in Type1 Diabetes: A Survey of the State-of-the-art.

Diabetes mellitus is a long-term chronicle disorder with a high prevalence rate worldwide. Continuous blood glucose and lifestyle monitoring enabled the control of blood glucose dynamics through machine learning applications using data created by various popular sensors. This survey aims to assess various classical time series, neural networks and state-of-the-art regression models based on a wide variety of machine learning techniques to predict blood glucose and hyper/hypoglycemia in Type 1 diabetic patients. The analysis covers blood glucose prediction modeling, regression, hyper/hypoglycemia alerts, diabetes diagnosis, monitoring, and management. However, the primary focus is on evaluating models for the prediction of Type 1 diabetes. A wide variety of machine learning algorithms have been explored to implement precision medicine by clinicians and provide patients with an early warning system. The automated pancreas may benefit from predictions and alerts of hyper and hypoglycemia.