Institute for Health & Aging, University of California San Francisco, San Francisco, CA, USA.
J Aging Health. 2023 Oct;35(9):677-687. doi: 10.1177/08982643221104369. Epub 2022 Jun 6.
The objective is to determine associations between stressors and pain across the late-life span.
Multilevel linear modeling was applied separately to harmonized repeated measures data from the Longitudinal Late-Life Health study (LLLH; = 342; 13-year interval) and the Health and Retirement Study (HRS; = 2959; 8-year interval).
In both the LLLH and HRS samples, independent of age, gender, and race, participants with higher average stressor levels experienced more numerous painful conditions and higher pain severity over the study intervals. In the HRS sample, they also experienced higher levels of pain interference. In general, participants' stressor levels did not influence rates of increase in their pain. Gender and race had few moderating effects on associations between stressors and pain.
Stressors and pain are associated across the late-life span. Future research should focus on the mediating mechanisms that account for this association and the moderating factors that affect its strength.
确定压力源与晚年疼痛之间的关联。
应用多层次线性模型分别对来自纵向老年健康研究(LLLH;n=342;13 年间隔)和健康与退休研究(HRS;n=2959;8 年间隔)的协调重复测量数据进行分析。
在 LLLH 和 HRS 样本中,无论年龄、性别和种族如何,压力源水平较高的参与者在研究期间经历了更多的疼痛状况和更高的疼痛严重程度。在 HRS 样本中,他们还经历了更高水平的疼痛干扰。一般来说,参与者的压力源水平并不影响他们疼痛的增长率。性别和种族对压力源与疼痛之间的关联仅有少数调节作用。
压力源与疼痛在晚年期间存在关联。未来的研究应关注解释这种关联的中介机制以及影响其强度的调节因素。