Neaderland M H, Riis R C, Rebhun W C, Erb H N
Am J Vet Res. 1987 Mar;48(3):427-30.
Corneal ulcers to the depth of the anterior third of the stroma were created surgically in both eyes of 10 ponies. One eye in each pony was treated topically with chloramphenicol and 1% atropine ophthalmic ointments 3 times per day; the contralateral eye was not treated topically. All ponies were given phenylbutazone orally for relief of ocular pain. Fluorescein-stained ulcers were measured once a day. The median healing time of the treated eyes (11 days) and the median healing time of the nontreated eyes (13.5 days) were found not to be significantly different. Clinically, however, more severe complications arose in the nontreated eyes.
在10匹小马的双眼上通过手术制造了深度达基质前三分之一的角膜溃疡。每匹小马的一只眼睛每天局部使用氯霉素和1%阿托品眼膏3次；对侧眼睛不进行局部治疗。所有小马口服保泰松以缓解眼部疼痛。每天测量一次荧光素染色的溃疡。发现治疗组眼睛的中位愈合时间（11天）和未治疗组眼睛的中位愈合时间（13.5天）没有显著差异。然而，临床上未治疗的眼睛出现了更严重的并发症。
