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头颈部骨化性脂肪瘤——综述。

Osteolipoma of head and neck - a review.

机构信息

Mid and South Essex NHS Foundation Trust, Broomfield Hospital, Department of Otolaryngology, Chelmsford, Essex, CM1 7ET, United Kingdom.

Mid and South Essex NHS Foundation Trust, Broomfield Hospital, Department of Otolaryngology, Chelmsford, Essex, CM1 7ET, United Kingdom.

出版信息

Braz J Otorhinolaryngol. 2022 Nov-Dec;88 Suppl 4(Suppl 4):S177-S187. doi: 10.1016/j.bjorl.2022.04.002. Epub 2022 May 20.

DOI:10.1016/j.bjorl.2022.04.002
PMID:35659712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9756048/
Abstract

OBJECTIVE

Due to the rarity of osteolipoma, current knowledge and understanding of its' clinical presentation, management, radiological features, histological characteristics, and prognosis are lacking and can present a clinical conundrum to clinicians and histopathologist alike, given wide range of differential diagnoses. This paper aims to compile, analyse and present details to augment the available literature on osteolipoma in the head and neck.

METHODS

A comprehensive literature search on PUBMED/MEDLINE, EMBASE, CINAHL and Science Citation Index, Google scholar and Cochrane database for osteolipoma in head and neck was performed up to the 1st May 2021. Reference lists from the relevant articles were then inspected and cross-referenced and any other pertinent publications were added to the review.

RESULTS

A total of 38 cases were identified from the literature. The commonest sites of involvement within the head and neck region were the oral cavity in 21 (56.8%) patients, followed by the neck in 7 (19.0%) patients. 29 (78.4%) patients presented with soft tissue swelling or mass making it the most common presenting feature. All patients had the tumour excised surgically; of which 18 (48.6%) were excised via transoral approach and 6 (16.2%) via open transcervical approach including 1 lateral pharyngotomy. 12 papers documented long-term follow-ups (median 12 months) with no recurrence. Only 1 regrowth was reported after 5-years.

CONCLUSIONS

Osteolipoma is a rare soft tissue neoplasm which has a wide range differential diagnosis including malignant processes. Recognising this benign tumour through an awareness of presenting sign and symptoms, radiological features and histopathology findings is important for patient reassurance as well as avoiding unnecessary radical treatment.

摘要

目的

由于骨脂瘤罕见,目前对其临床表现、治疗、影像学特征、组织学特征和预后的认识有限,由于广泛的鉴别诊断,这可能给临床医生和组织病理学家带来临床难题。本文旨在收集、分析和提供详细信息,以增加有关头颈部骨脂瘤的现有文献。

方法

对 PUBMED/MEDLINE、EMBASE、CINAHL 和科学引文索引、Google 学术和 Cochrane 数据库进行了全面的文献检索,以查找头颈部骨脂瘤的文献,检索时间截至 2021 年 5 月 1 日。然后检查和交叉引用相关文章的参考文献,并添加任何其他相关出版物进行综述。

结果

从文献中总共确定了 38 例病例。头颈部最常见的受累部位是口腔,21 例(56.8%)患者,其次是颈部 7 例(19.0%)患者。29 例(78.4%)患者表现为软组织肿胀或肿块,这是最常见的表现特征。所有患者均通过手术切除肿瘤;其中 18 例(48.6%)通过经口入路切除,6 例(16.2%)通过开放式经颈入路切除,包括 1 例侧咽切开术。12 篇文献记录了长期随访(中位数 12 个月),无复发。仅 1 例在 5 年后报告复发。

结论

骨脂瘤是一种罕见的软组织肿瘤,其鉴别诊断范围广泛,包括恶性肿瘤。通过对临床表现、影像学特征和组织病理学发现的认识,认识到这种良性肿瘤对患者的安心以及避免不必要的激进治疗非常重要。

相似文献

1
Osteolipoma of head and neck - a review.头颈部骨化性脂肪瘤——综述。
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本文引用的文献

1
Intraparotid Osteolipoma: Treatment Option and Surgical View.腮腺内骨脂瘤:治疗选择和手术视角。
J Craniofac Surg. 2021;32(5):1894-1897. doi: 10.1097/SCS.0000000000007519.
2
Osteolipoma: a review of the literature and a rare case report.骨脂瘤:文献复习及罕见病例报告。
Oral Radiol. 2021 Oct;37(4):560-565. doi: 10.1007/s11282-020-00500-8. Epub 2021 Jan 11.
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Retropharyngeal Osteolipoma Requiring an Interdisciplinary Approach.
Ear Nose Throat J. 2022 May;101(4):231-233. doi: 10.1177/0145561320954131. Epub 2020 Aug 30.
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Osteolipoma: An Extremely Rare Hard Palate Tumor.骨脂瘤:一种极其罕见的硬腭肿瘤。
Cureus. 2020 May 15;12(5):e8146. doi: 10.7759/cureus.8146.
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Osteolipoma in the retromolar trigone: A case report and review of literature.磨牙后三角区骨脂瘤:一例报告并文献复习
Ann Maxillofac Surg. 2016 Jul-Dec;6(2):304-307. doi: 10.4103/2231-0746.200349.
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Osteolipoma of the buccal mucosa: a case report.颊黏膜骨脂肪瘤:一例报告
Aust Dent J. 2017 Sep;62(3):378-381. doi: 10.1111/adj.12502. Epub 2017 May 31.
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"Osteolipoma of buccal mucosa: Case report and literature review".颊黏膜骨脂瘤:病例报告及文献综述
J Clin Exp Dent. 2016 Apr 1;8(2):e214-8. doi: 10.4317/jced.52803. eCollection 2016 Apr.
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A huge osteolipoma involving the coronoid process: a case report.
J Oral Sci. 2016;58(1):141-4. doi: 10.2334/josnusd.58.141.
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Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?间充质干细胞的命运抉择:脂肪细胞还是成骨细胞?
Cell Death Differ. 2016 Jul;23(7):1128-39. doi: 10.1038/cdd.2015.168. Epub 2016 Feb 12.
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Osteolipoma: a rare tumor in the oral cavity.骨脂肪瘤:口腔内一种罕见的肿瘤。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Jul;122(1):e8-e13. doi: 10.1016/j.oooo.2015.09.013. Epub 2015 Sep 28.