Department of Pharmacology, Faculty of Medicine, Sabaragamuwa University of Sri Lanka, Hidellana, Ratnapura, Sri Lanka.
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lanka.
J Med Case Rep. 2022 Jun 4;16(1):218. doi: 10.1186/s13256-022-03442-3.
Hump-nosed pit viper is a medically important deadly venomous snake in Sri Lanka and is the commonest cause of venomous snakebites in the country. It frequently causes local effects and systemic manifestations such as acute kidney injury and coagulopathy that occur in less than 10% of all bites. This also includes some atypical presentations such as thrombotic microangiopathy and myocardial infarction. Currently, no antivenom is available for hump-nosed pit viper bites in Sri Lanka, and patients are managed with supportive treatment. This case illustrates an acute ischemic stroke following a hump-nosed viper bite, which is the second case in the literature.
A 71-year-old a Sinhalese male patient presented with left-sided hemiparesis with mouth deviation on day 2 of hump-nosed viper (Hypnale spp.) bite on the right foot. Non-contrast computed tomography of brain showed right ischemic stroke in internal capsule. He was given antiplatelets and statins and continued supportive treatment including limb physiotherapy and speech therapy. He recovered completely and was discharged on day 4 with clinic follow-up.
Physicians should be aware that ischemic cerebral infarcts may occur following hump-nosed pit viper bites.
圆鼻巨蜥是斯里兰卡一种具有重要医学意义的致命毒蛇,也是该国毒蛇咬伤的最常见原因。它经常引起局部和全身表现,如急性肾损伤和凝血功能障碍,这些情况在所有咬伤中不到 10%。这还包括一些非典型表现,如血栓性微血管病和心肌梗死。目前,斯里兰卡还没有针对圆鼻巨蜥咬伤的抗蛇毒血清,患者只能接受支持性治疗。本例说明了圆鼻巨蜥咬伤后发生急性缺血性卒中,这是文献中的第二例。
一名 71 岁的僧伽罗男性患者,在右脚被圆鼻巨蜥(Hypnale spp.)咬伤后第 2 天出现左侧偏瘫和口角偏斜。头部非对比 CT 显示内囊右侧缺血性卒中。给予抗血小板和他汀类药物治疗,并继续给予包括肢体物理治疗和言语治疗在内的支持性治疗。他完全康复,于第 4 天出院,进行门诊随访。
医生应意识到圆鼻巨蜥咬伤后可能会发生缺血性脑梗死。