Salehi Mohammadreza, Nourbakhsh Seyed Mohammad Kazem, Ardakani Mohammad Vahedian, Abdollahi Alireza, Khaki Pegah Afarinesh, Aliramezani Amir
Department of Infectious Diseases and Tropical Medicines, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pediatrics, Pediatric Hematology and Oncology Section, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Int J Surg Case Rep. 2022 Jun;95:107202. doi: 10.1016/j.ijscr.2022.107202. Epub 2022 May 17.
Nontyphoidal Salmonella infection can lead to gastroenteritis, enteric fever, and bacteremia. However, joint infections due to this bacterium are rare, and usually associated with immunosuppressive disorders.
A 16-year-old girl, with a recent history of acute lymphocytic leukemia (ALL) presented with bacteremia, and bilateral hip pain after COVID-19 symptoms. Clinical presentation, laboratory features and imaging showed bilateral nontyphoidal Salmonella septic arthritis. We administered antibiotics, based on antibiotics susceptibility pattern of the isolated Salmonella.
The case is presented because reports of bilateral hip joint infection due to nontyphoidal Salmonella are rare especially after COVID-19. When the patient presents with joint discomfort, the clinician should think infection especially in immunocompromised hosts.
It illustrates successful management of septic arthritis requires prompt clinical diagnosis, microorganism identification, administration of appropriate systemic antibiotics and hip joint surgery.
非伤寒沙门氏菌感染可导致肠胃炎、伤寒热和菌血症。然而,这种细菌引起的关节感染很少见,通常与免疫抑制性疾病有关。
一名16岁女孩,近期有急性淋巴细胞白血病(ALL)病史,在出现新冠症状后出现菌血症和双侧髋关节疼痛。临床表现、实验室检查结果和影像学检查显示为双侧非伤寒沙门氏菌感染性关节炎。我们根据分离出的沙门氏菌的药敏模式给予抗生素治疗。
之所以呈现该病例,是因为非伤寒沙门氏菌引起双侧髋关节感染的报告很少见,尤其是在新冠之后。当患者出现关节不适时,临床医生应考虑感染,尤其是在免疫功能低下的宿主中。
这表明感染性关节炎的成功治疗需要及时的临床诊断、微生物鉴定、给予适当的全身性抗生素以及髋关节手术。