Dower Joshua, Lerner David P, Geva Tamar, Wener Kenneth
Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA.
Lahey Hospital and Medical Center, 41 Burlington Mall Road, Burlington, MA 01805, USA.
Case Rep Infect Dis. 2018 May 21;2018:4874575. doi: 10.1155/2018/4874575. eCollection 2018.
meningitis is a rare infection, particularly in adults. We report the case of a 75-year-old female with a history of rheumatoid arthritis on TNF-antagonist immunosuppressive therapy who initially presented to the hospital for management of back and leg pain and was ultimately diagnosed with bacterial meningitis secondary to species infection. She was treated with ceftriaxone with slow improvement in neurological function. Though the source of infection was never clearly identified from multiple imaging studies, we suspect the severity of her presentation was due to her history of TNF-antagonist use.
脑膜炎是一种罕见的感染性疾病，在成年人中尤为少见。我们报告了一例75岁女性患者，该患者有类风湿关节炎病史，正在接受肿瘤坏死因子拮抗剂免疫抑制治疗，最初因背部和腿部疼痛入院治疗，最终被诊断为继发于某种细菌感染的细菌性脑膜炎。她接受了头孢曲松治疗，神经功能有缓慢改善。尽管通过多项影像学检查从未明确确定感染源，但我们怀疑她病情严重是由于使用肿瘤坏死因子拮抗剂的病史所致。
