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[颊肌:肉毒杆菌毒素注射治疗面瘫后遗症的新靶点]

[Buccinator muscle: A new target for botulinum toxin injections in the treatment of facial paralysis sequelae].

作者信息

Lacroix G, Duquennoy-Martinot V, Guerreschi P

机构信息

Service de chirurgie plastique, CHU de Lille, hôpital Salengro, 59037 Lille cedex, France.

出版信息

Ann Chir Plast Esthet. 2022 Jun;67(3):125-132. doi: 10.1016/j.anplas.2022.04.001. Epub 2022 May 31.

DOI:10.1016/j.anplas.2022.04.001
PMID:35662477
Abstract

AIM OF THE STUDY

Facial paralysis can cause aesthetic and functional sequelae such as spasms and synkinesis. Botulinum toxin injection is one of the key treatments for these sequelae. Its use is widely reported in the literature for many muscles of the face but little for the buccinator muscle. However, its hyperactivity can be disabling, generating chewing and smile disorders in particular. The aim of this prospective study is to report the effects of botulinum toxin using a questionnaire specifically for the buccinator muscle.

PATIENTS AND METHODS

The study was conducted on 13 patients. The facial paralysis was of various origins. The questionnaire consisted of 10 questions each assessing a facial mimic involving the buccinator muscle. The rating scale ranged from -10 (major deterioration) to 10 (major improvement) for each question. The evaluation was done at 1 and 4 months after the injection. We found an improvement for all the mimics and gestures evaluated (0 to 7.38 at 1 month and 0.15 to 6.62 at 4 months). This improvement was greater at 1 month than at 4 months. Few side effects were reported.

CONCLUSION

Botulinum toxin injections are an effective, safe therapeutic solution for the treatment of the facial paralysis sequelae of the buccinator muscle through a new specific questionnaire. Subsequently, it would be interesting to carry out an evaluation on a larger population and to compare it with other recognized scores in facial paralysis.

摘要

研究目的

面瘫可导致诸如痉挛和联带运动等美学和功能后遗症。肉毒杆菌毒素注射是治疗这些后遗症的关键方法之一。文献中广泛报道了其在面部许多肌肉中的应用,但在颊肌方面的报道较少。然而,颊肌功能亢进可能会使人丧失能力,尤其会导致咀嚼和微笑障碍。这项前瞻性研究的目的是通过一份专门针对颊肌的问卷来报告肉毒杆菌毒素的效果。

患者与方法

该研究对13名患者进行。面瘫病因各异。问卷由10个问题组成,每个问题评估一个涉及颊肌的面部表情。每个问题的评分范围从-10(严重恶化)到10(显著改善)。评估在注射后1个月和4个月进行。我们发现所有评估的表情和动作均有改善(1个月时为0至7.38,4个月时为0.15至6.62)。1个月时的改善比4个月时更大。报告的副作用很少。

结论

通过一种新的特定问卷,肉毒杆菌毒素注射是治疗颊肌面瘫后遗症的一种有效、安全的治疗方法。随后,对更大规模人群进行评估并与面瘫的其他公认评分进行比较将是很有意义的。

相似文献

1
[Buccinator muscle: A new target for botulinum toxin injections in the treatment of facial paralysis sequelae].[颊肌:肉毒杆菌毒素注射治疗面瘫后遗症的新靶点]
Ann Chir Plast Esthet. 2022 Jun;67(3):125-132. doi: 10.1016/j.anplas.2022.04.001. Epub 2022 May 31.
2
Outcomes of Buccinator Treatment With Botulinum Toxin in Facial Synkinesis.颊肌肉毒毒素治疗面部联动的疗效。
JAMA Facial Plast Surg. 2018 May 1;20(3):196-201. doi: 10.1001/jamafacial.2017.1385.
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Buccinator synkinesis treated by botulinum toxin in facial palsy and hemifacial spasms.咀嚼肌联带运动在面瘫和半面痉挛中采用肉毒毒素治疗。
J Plast Reconstr Aesthet Surg. 2021 Jul;74(7):1464-1469. doi: 10.1016/j.bjps.2020.12.002. Epub 2020 Dec 5.
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Treating Buccinator With Botulinum Toxin in Patients With Facial Synkinesis: A Previously Overlooked Target.对面部联动患者使用肉毒杆菌毒素治疗咬肌:一个此前被忽视的靶点。
Ophthalmic Plast Reconstr Surg. 2016 Mar-Apr;32(2):138-41. doi: 10.1097/IOP.0000000000000449.
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Botulinum toxin treatment of the buccinator muscle facial synkinesis: A systematic review.肉毒杆菌毒素治疗颊肌面联带运动:系统评价。
J Plast Reconstr Aesthet Surg. 2023 Nov;86:88-93. doi: 10.1016/j.bjps.2023.08.006. Epub 2023 Aug 19.
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[Facial palsy sequel and botulinum toxin].[面瘫后遗症与肉毒杆菌毒素]
Ann Chir Plast Esthet. 2015 Oct;60(5):377-92. doi: 10.1016/j.anplas.2015.07.011. Epub 2015 Oct 1.
7
Re: "Treating Buccinator with Botulinum Toxin in Patients with Facial Synkinesis: A Previously Overlooked Target".关于:“肉毒杆菌毒素治疗面部联带运动患者的颊肌:一个先前被忽视的靶点”
Ophthalmic Plast Reconstr Surg. 2016 Jan-Feb;32(1):70. doi: 10.1097/IOP.0000000000000608.
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Botulinum Toxin Type A Injection in the Treatment of Postparetic Facial Synkinesis: An Integrative Review.A型肉毒毒素注射治疗面瘫后面部联动:综合评价。
Am J Phys Med Rehabil. 2022 Mar 1;101(3):284-293. doi: 10.1097/PHM.0000000000001840.
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Reply re: "Treating Buccinator with Botulinum Toxin in Patients with Facial Synkinesis: A Previously Overlooked Target".回复关于“肉毒杆菌毒素治疗面部联动患者的咬肌:一个先前被忽视的靶点”。
Ophthalmic Plast Reconstr Surg. 2016 Jan-Feb;32(1):70-1. doi: 10.1097/IOP.0000000000000609.
10
Epidemiologic Overview of Synkinesis in 353 Patients with Longstanding Facial Paralysis under Treatment with Botulinum Toxin for 11 Years.353例长期面瘫患者接受肉毒杆菌毒素治疗11年的联带运动流行病学概述
Plast Reconstr Surg. 2015 Dec;136(6):1289-1298. doi: 10.1097/PRS.0000000000001802.

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