Busch Brandon H, Wilhelm David, Johnson Paul, Pfeifer Mark
Internal Medicine, University of Louisville, Louisville, USA.
Cureus. 2022 May 3;14(5):e24711. doi: 10.7759/cureus.24711. eCollection 2022 May.
Granulomatosis with Polyangiitis is a rare autoimmune vasculitis that is classically characterized by effects on the upper respiratory tract, lungs, and kidneys. Delay in diagnosis is often attributed to variable and sequential presentation of symptoms rather than concurrent symptomatology. It is important to recognize the wide range of initial presenting symptoms as early diagnosis and treatment is critical in preventing potentially irreversible damage resulting from delayed diagnosis. We present a case of a 29-year-old male with history of mixed sensorineural-conductive hearing loss presumed to be secondary to chronic otitis media who presented to the emergency department with complaint of hematemesis with a subsequent diagnosis of granulomatosis with polyangiitis.
肉芽肿性多血管炎是一种罕见的自身免疫性血管炎，其典型特征是对上呼吸道、肺部和肾脏产生影响。诊断延迟通常归因于症状的多变性和相继出现，而非同时出现多种症状。认识到广泛的初始症状表现很重要，因为早期诊断和治疗对于预防因诊断延迟导致的潜在不可逆损害至关重要。我们报告一例29岁男性病例，该患者有混合性感音神经性-传导性听力损失病史，推测继发于慢性中耳炎，因呕血就诊于急诊科，随后被诊断为肉芽肿性多血管炎。
