Lobao Madalena, Sampaio Maria Beatriz, Sousa Leite Miguel, Gomes Felisbela, Silva Joao M
Internal Medicine, Hospital de Santo Antonio dos Capuchos, Centro Hospitalar Universitario de Lisboa Central (CHULC), Lisbon, PRT.
Internal Medicine, Hospital de Santo Antionio dos Capuchos, Centro Hospitalar Universitario de Lisboa Central (CHULC), Lisbon, PRT.
Cureus. 2022 May 3;14(5):e24692. doi: 10.7759/cureus.24692. eCollection 2022 May.
A 30-year-old Turkish male was found lethargic and surrounded by vomit. At the hospital, severe hypernatremic dehydration and acute kidney failure were evident. His conscious level improved with fluid resuscitation. A differential diagnosis of altered mental status was considered. A complete clinical triad of Wernicke encephalopathy (WE), supported by MRI findings, was compatible with thiamine deficiency. Previous bariatric surgery was later confirmed. Despite no clinical signs of heart failure, a high level of NT-proBNP (N-terminal prohormone brain natriuretic peptide) and a dilated, hypokinetic myocardiopathy detected on the echocardiogram led us to assume beri-beri heart disease. High-dose intravenous thiamine, ACE (angiotensin conversing enzyme) inhibitors, beta-blockers, and physical therapy were initiated with remarkable improvement in his clinical condition.
一名30岁的土耳其男性被发现精神萎靡,周围有呕吐物。在医院,明显存在严重的高钠血症性脱水和急性肾衰竭。经液体复苏后,他的意识水平有所改善。考虑了精神状态改变的鉴别诊断。由MRI结果支持的韦尼克脑病(WE)完整临床三联征与硫胺素缺乏相符。后来证实他曾接受过减肥手术。尽管没有心力衰竭的临床体征,但超声心动图检测到的高水平NT-proBNP(N端前脑钠肽)和扩张性、运动减弱性心肌病使我们推测为脚气性心脏病。开始使用大剂量静脉注射硫胺素、ACE(血管紧张素转换酶)抑制剂、β受体阻滞剂和物理治疗,他的临床状况有了显著改善。