Fessatidis I, Hackett D, Oakley C M, Sapsford R N, Bentall H H
Ann Thorac Surg. 1987 Apr;43(4):368-72. doi: 10.1016/s0003-4975(10)62805-6.
From 1974 through 1983, 689 hospital survivors of Starr-Edwards (SE) valve replacement were identified; 279 (40.4%) patients with complete follow-up had an isolated mitral valve (SE model 6120 or 6400) replacement: 60.6% of these patients were women, 33.4% were in sinus rhythm, 32.3% had predominantly mitral stenosis, and 23.6% had predominantly regurgitation. Forty-six (6.7%) patients had mitral and aortic valve (SE model 1260 or 2400) replacement, 60.9% were women, and 13% were in sinus rhythm. To determine the long-term outcome of these SE valve prostheses, 325 (97.8%) patients were observed for up to 10 years. Total 10-year mortality was 40 patients (2.54% patients/yr) in the mitral group, of which 26 deaths (9.3%) were cardiac in origin; 8 deaths (2.8%) were directly valve related. Eight patients died (3.47% patients/yr) in the double-valve group, of which 5 deaths (10.8%) had a cardiac cause; 2 deaths (4.3%) were directly valve related. Primary valve failure was never proved. Actuarial estimates of survival at 10 years were 82 +/- 2.6% for the mitral valve group and 81 +/- 6% for the double-valve group. Actuarial estimates of freedom from valve-related morbidity were 87 +/- 2% for the mitral valve group and 59 +/- 7% for the double-valve group. Actuarial estimates of freedom from thromboembolism were 93 +/- 2% for the mitral valve group and 70 +/- 7% for the double-valve group. This prosthesis-based assessment has shown satisfactory long-term performance characteristics of the SE mitral models 6120 and 6400 without any recorded episodes of mechanical valve dysfunctions.
1974年至1983年期间，共确定了689例接受斯塔尔-爱德华兹（SE）瓣膜置换术的医院幸存者；279例（40.4%）有完整随访资料的患者接受了单纯二尖瓣置换术（SE型号6120或6400）：这些患者中60.6%为女性，33.4%为窦性心律，32.3%以二尖瓣狭窄为主，23.6%以二尖瓣反流为主。46例（6.7%）患者接受了二尖瓣和主动脉瓣置换术（SE型号1260或2400），60.9%为女性，13%为窦性心律。为了确定这些SE瓣膜假体的长期结果，对325例（97.8%）患者进行了长达10年的观察。二尖瓣组10年总死亡率为40例（2.54%/年），其中26例死亡（9.3%）源于心脏；8例死亡（2.8%）与瓣膜直接相关。双瓣组有8例患者死亡（3.47%/年），其中5例死亡（10.8%）由心脏原因导致；2例死亡（4.3%）与瓣膜直接相关。从未证实有原发性瓣膜功能衰竭。二尖瓣组10年生存的精算估计值为82±2.6%，双瓣组为81±6%。二尖瓣组无瓣膜相关并发症的精算估计值为87±2%，双瓣组为59±7%。二尖瓣组无血栓栓塞的精算估计值为93±2%，双瓣组为70±7%。这种基于假体的评估显示，SE二尖瓣型号6120和6400具有令人满意的长期性能特征，没有任何机械瓣膜功能障碍的记录事件。
