肿瘤整形外科技术与传统修复技术在颌面肿瘤切除术后大面积皮肤缺损修复中的应用:一项随机对照试验

The Tumor Plastic Surgery Technology versus Traditional Repair Technology on the Repair of Large-Area Skin Defects after Maxillofacial Tumor Resection: A Randomized Controlled Trial.

作者信息

Zhang Xue-Feng, Chu Zheng, Yang Hong-Li, Zhao Bing

机构信息

Department of Orthopedics, Panzhihua Iron and Steel Group General Hospital, Panzhihua, Sichuan Province, China.

Department of Neurosurgery, Panzhihua Iron and Steel Group General Hospital, Panzhihua, Sichuan Province, China.

出版信息

J Oncol. 2022 May 26;2022:3004695. doi: 10.1155/2022/3004695. eCollection 2022.

Abstract

OBJECTIVE

To explore the effect of tumor plastic surgery on the repair of large-area skin defects after maxillofacial tumor resection.

METHODS

90 patients undergoing maxillofacial tumor resection in our hospital from March 2019 to March 2020 were selected and randomized 1 : 1 to receive either tumor plastic surgery (experimental group) or traditional repair (control group). The clinical efficacy and facial cosmetic improvement of the two groups were compared. The Patient and Observer Scar Assessment Scale (POSAS) was used to evaluate the surgical outcomes of the two groups, the Profile of Mood States (POMS) was used to evaluate the patients' psychological status, and the Generic Quality of Life Inventory-74 (GQOLI-74) was used to assess the quality of life of patients.

RESULTS

Total clinical effective rate of the experimental group was significantly higher than that of the control group ( < 0.001). A higher excellent rate of facial cosmetic improvement was observed in the experimental group versus the control group ( < 0.001). Significantly lower POSAS scores of the experimental group than the control group were observed ( < 0.001). The POMS scores of the experimental group after treatment were lower than those of the control group ( < 0.001). Tumor plastic surgery resulted in a remarkably higher GQOLI-74 score in the patients versus traditional repair ( < 0.001).

CONCLUSION

Tumor plastic surgery is a promising alternative for patients undergoing maxillofacial tumor resection. It can effectively promote the recovery of facial morphology and physiological function of patients, with high clinical efficacy, so it merits promotion and application.

摘要

目的

探讨肿瘤整形手术对颌面部肿瘤切除术后大面积皮肤缺损修复的效果。

方法

选取2019年3月至2020年3月在我院接受颌面部肿瘤切除术的90例患者,按1∶1随机分为肿瘤整形手术组(试验组)和传统修复组(对照组)。比较两组的临床疗效及面部美容改善情况。采用患者和观察者瘢痕评估量表(POSAS)评估两组手术效果,采用情绪状态量表(POMS)评估患者心理状态,采用生活质量综合评定问卷74(GQOLI - 74)评估患者生活质量。

结果

试验组总临床有效率显著高于对照组(<0.001)。试验组面部美容改善优良率高于对照组(<0.001)。试验组POSAS评分显著低于对照组(<0.001)。试验组治疗后的POMS评分低于对照组(<0.001)。与传统修复相比,肿瘤整形手术使患者的GQOLI - 74评分显著更高(<0.001)。

结论

肿瘤整形手术是颌面部肿瘤切除患者的一种有前景的选择。它能有效促进患者面部形态和生理功能的恢复,临床疗效高,值得推广应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77a0/9162858/6c9c20a0a87b/JO2022-3004695.001.jpg

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