Guerini Camilla, Lenti Marco Vincenzo, Rossi Chiara, Arpa Giovanni, Peri Andrea, Gallotti Anna, Di Sabatino Antonio, Vanoli Alessandro
Unit of Anatomic Pathology, Department of Molecular Medicine, University of Pavia, and IRCCS San Matteo Hospital Foundation, Pavia, Italy.
First Department of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Front Med (Lausanne). 2022 May 19;9:890794. doi: 10.3389/fmed.2022.890794. eCollection 2022.
Autoimmune gastritis is a chronic immune-mediated disorder characterized by varied clinical manifestations and that should be endoscopically managed over time, as the gastric atrophy contributes to microenvironmental alterations of the stomach milieu, and an increased cancer risk has been linked to this condition. Here, we report the unusual case of a woman who developed a cardiac high-grade pyloric adenoma in a context of previously undiagnosed autoimmune gastritis with synchronous neuroendocrine cell hyperplastic and dysplastic lesions.
自身免疫性胃炎是一种慢性免疫介导性疾病，其临床表现多样，且随着时间推移需通过内镜进行管理，因为胃萎缩会导致胃内微环境改变，并且这种情况与癌症风险增加有关。在此，我们报告一例罕见病例，一名女性在先前未诊断出的自身免疫性胃炎背景下发生了贲门部高级别幽门腺瘤，并伴有同步的神经内分泌细胞增生和发育异常病变。
