Ioseliani G D, Chilaia S M, Guskov I A, Chkhaidze Z A, Dvaladze G A, Khodeli N G, Khmelevskoi L E
Artif Organs. 1987 Feb;11(1):31-8. doi: 10.1111/j.1525-1594.1987.tb02623.x.
Using a new heart-lung machine developed at our Institute, experiments were conducted on dogs, donkeys, and monkeys, providing complete and assisted artificial circulation, assisted oxygenation, and perfusion preservation of the heart. The new apparatus consists of two sequentially mounted artificial ventricles working in an antiphase mode; blood oxygenation is accomplished by a reusable oxygenator with a fluorocarbon preoxygenator. Experimental results indicate that clinical use of the apparatus is promising and deserves consideration. The conditions of perfusion were close to physiological conditions and provided long-term survival of the animals. Performance in left ventricular bypass was optimized by monitoring myocardial PO2 and the state of the quick-connect/cut-off assemblies.
利用我们研究所研发的新型心肺机，在狗、驴和猴子身上进行了实验，实现了完全和辅助人工循环、辅助氧合以及心脏灌注保存。新装置由两个以反相模式工作的顺序安装的人工心室组成；血液氧合通过带有氟碳预氧合器的可重复使用的氧合器完成。实验结果表明，该装置的临床应用前景广阔，值得考虑。灌注条件接近生理条件，确保了动物的长期存活。通过监测心肌PO2和快速连接/切断组件的状态，优化了左心室旁路的性能。
