From Spectrum Health Plastic Surgery Residency; and Partners in Plastic Surgery.
Plast Reconstr Surg. 2022 Aug 1;150(2):270-280. doi: 10.1097/PRS.0000000000009340. Epub 2022 Jun 3.
The indications for nipple-sparing mastectomy have broadened over time. Patients undergoing nipple-sparing mastectomy who have enlarged or ptotic breasts are at risk for skin flap and/or nipple-areola complex necrosis. Premastectomy mastopexy or breast reduction may reduce the risk for these complications.
A retrospective review was undertaken in a series of patients who underwent premastectomy reduction mammaplasty or mastopexy followed by nipple-sparing mastectomy and immediate staged tissue expander/implant-based breast reconstruction. In each case, a subnipple biopsy was performed at the premastectomy procedure to clear it of any potential malignant involvement. In addition, the area under the areola was undermined to maximize the effect of the delay phenomenon on the eventual survival of the nipple-areola complex. Final reconstruction involved tissue expander exchange for a permanent implant with associated fat grafting. Data regarding surgical timing and selected postoperative complications were recorded.
In total, 39 implant-based reconstructions were performed in 20 patients. There were no cases of mastectomy flap necrosis, and partial necrosis of the nipple-areola complex with delayed wound healing was seen in two breasts in the same patient. All patients eventually completed the reconstructive process successfully.
Premastectomy mastopexy or breast reduction may afford a protective effect against mastectomy flap or nipple-areola complex necrosis in patients with large or ptotic breasts who subsequently undergo nipple-sparing mastectomy with immediate breast reconstruction.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
随着时间的推移,保乳头乳晕乳房切除术的适应证已经扩大。对于接受保乳头乳晕乳房切除术且乳房较大或下垂的患者,存在皮瓣和/或乳头乳晕复合体坏死的风险。术前乳房缩小术或乳房提升术可能会降低这些并发症的风险。
对一组接受术前乳房缩小成形术或乳房提升术,然后行保乳头乳晕乳房切除术和即刻分期组织扩张器/植入物乳房重建的患者进行了回顾性研究。在每种情况下,均在术前手术时进行乳晕下活检,以清除任何潜在的恶性浸润。此外,乳晕下的区域被切开,以最大限度地发挥延迟现象对最终乳头乳晕复合体存活的影响。最终的重建涉及组织扩张器更换为永久性植入物,并进行相关的脂肪移植。记录了手术时机和选定的术后并发症相关数据。
总共对 20 名患者的 39 个植入物重建进行了研究。没有乳房切除术皮瓣坏死的病例,在同一患者的两个乳房中观察到乳头乳晕复合体部分坏死伴延迟愈合。所有患者最终均成功完成了重建过程。
对于随后接受保乳头乳晕乳房切除术和即刻乳房重建且乳房较大或下垂的患者,术前乳房提升术或乳房缩小术可能对乳房切除术皮瓣或乳头乳晕复合体坏死起到保护作用。
临床问题/证据水平:治疗性,IV 级。