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视网膜母细胞瘤破裂:罕见病例的处理。

Ruptured retinoblastoma: management in a rare case scenario.

机构信息

Narayana Nethralaya, Bangalore, India.

Narayana Nethralaya, Bangalore, India

出版信息

BMJ Case Rep. 2022 Jun 6;15(6):e248830. doi: 10.1136/bcr-2022-248830.

Abstract

A preschool child presented with white reflex in left eye since 2 months. Examination under anaesthesia revealed left eye retinoblastoma group D as per international classification of retinoblastoma. In collaboration with medical oncologist, systemic chemotherapy was started. After two cycles of systemic chemotherapy, tumour ruptured into the vitreous cavity suspending the tumour cells in the vitreous jelly. After a combination of systemic and intravitreal chemotherapy with adjuvant transpupillary thermotherapy of the residual retinal tumour, retinoblastoma regressed completely with corresponding flat scar.

摘要

一个 2 个月大的学龄前儿童左眼出现白色反光。全身麻醉检查显示左眼视网膜母细胞瘤符合国际视网膜母细胞瘤分类的 D 组。与肿瘤内科医生合作,开始进行全身化疗。全身化疗两个周期后,肿瘤破裂进入玻璃体腔,使肿瘤细胞悬浮在玻璃体凝胶中。在全身化疗和玻璃体内化疗联合辅助残余视网膜肿瘤经瞳孔温热疗法后,视网膜母细胞瘤完全消退,相应的扁平瘢痕形成。

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本文引用的文献

1
Cavitary retinoblastoma: clinical observations.空洞性视网膜母细胞瘤:临床观察。
Eye (Lond). 2020 Apr;34(4):704-710. doi: 10.1038/s41433-019-0581-1. Epub 2019 Sep 18.
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Current update on retinoblastoma.视网膜母细胞瘤的最新进展
Int Ophthalmol Clin. 2011 Winter;51(1):77-91. doi: 10.1097/IIO.0b013e3182010f29.
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Surv Ophthalmol. 1981 May-Jun;25(6):347-72. doi: 10.1016/0039-6257(81)90072-2.

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