亮氨酸的非钠依赖性突触体摄取。

Sodium-independent synaptosomal uptake of leucine.

作者信息

Tan C H, Leong M K, Ng F H, Thiyagarajah P

出版信息

Biochem Int. 1987 Jan;14(1):161-6.

Abstract

The uptake of leucine by rat brain synaptosomes was investigated in a Na+-free medium. It was found that leucine was transported into synaptosomes by 2 uptake processes which were both extremely sensitive to inhibition by 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid. These 2 components were distinguishable from each other by kinetic analysis and by their relative sensitivity to inhibition by selected amino acids.

摘要

在无钠培养基中研究了大鼠脑突触体对亮氨酸的摄取。结果发现，亮氨酸通过两种摄取过程转运到突触体中，这两种过程对2-氨基双环-(2,2,1)-庚烷-2-羧酸的抑制都极为敏感。通过动力学分析以及它们对选定氨基酸抑制的相对敏感性，可以区分这两种成分。