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西班牙核医学和分子影像学学会(SEMNIM)放射性导向手术工作组(GTCRG-RGSWG)的调查:使用或不使用选择性前哨淋巴结活检适应证的不可触及乳腺病变的放射性导向定位:ROLL、SNOLL 和 I 种子。

Survey of the Radioguided Surgery Working Group (GTCRG-RGSWG) of the Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM): Radioguided localization of non-palpable breast lesions with or without indication for selective sentinel node biopsy: ROLL, SNOLL and I seeds.

机构信息

Servicio de Medicina Nuclear, Hospital Universitario Virgen Macarena, Sevilla, Spain; Grupo de Trabajo de Cirugía Radioguiada (GTCRG) de la Sociedad Española de Medicina Nuclear e Imagen Molecular (SEMNIM), Spain.

Servicio de Medicina Nuclear, Hospital Universitario Joan XXIII de Tarragona, Tarragona, Spain; Grupo de Trabajo de Cirugía Radioguiada (GTCRG) de la Sociedad Española de Medicina Nuclear e Imagen Molecular (SEMNIM), Spain.

出版信息

Rev Esp Med Nucl Imagen Mol (Engl Ed). 2022 Jul-Aug;41(4):223-230. doi: 10.1016/j.remnie.2022.05.014. Epub 2022 Jun 3.

Abstract

OBJECTIVE

To know the current status of the technique of radioguided localisation of non-palpable breast lesions with or without indication for selective sentinel node biopsy -ROLL, SNOLL and I seeds- by conducting a national survey developed by the Working Group on Radioguided Surgery (GTCRG) of the Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM).

MATERIAL AND METHODS

In October 2020, the form was sent in digital format to the different nuclear medicine services in Spain. A response time of 2 months with an overtime of 15 days was given. The number of ROLL/SNOLL procedures in each centre and the methodology used were obtained, including important technical details. In addition, a specific section on I seeds was included. The results were automatically downloaded into an Excel 2007 spreadsheet for subsequent analysis with the same program.

RESULTS

The survey was answered by 55 centres; 21 use wire-guided localisation while the remaining 34 use different radioguided surgery techniques (RGS) for the localisation of non-palpable breast lesions, with the results itemized into thirteen sections. The commonly used tracer dose is 111 MBq for the ROLL technique and 222 MBq for the SNOLL technique, with a volume of 0.2 ml. The most common protocol is the two-day protocol. 26% of centres performing CRG use I seeds for both breast lesion and suspicious/pathological node detection, with the time between implantation and removal being about 3 days, with subsequent radiological control in most cases.

CONCLUSION

The survey shows the relevance of radioguided surgery in the management of breast cancer patients at different stages of the disease, with disparity in the implementation of new techniques and tools, which responds to the multiple healthcare realities of Nuclear Medicine services.

摘要

目的

通过开展由西班牙核医学与分子影像学会(SEMNIM)放射性外科工作组(GTCRG)开发的全国性调查,了解在有或无选择性前哨淋巴结活检指征的情况下,应用放射性核素引导下定位技术(ROLL、SNOLL 和 I 种子)定位不可触及乳腺病变的当前现状。

材料与方法

2020 年 10 月,以数字格式向西班牙各地的核医学服务机构发送了该表格。设定了 2 个月的回复时间,并可额外延长 15 天。获取了每个中心的 ROLL/SNOLL 手术数量和使用的方法,包括重要的技术细节。此外,还包含了 I 种子的专门部分。结果自动下载到 Excel 2007 电子表格中,以便随后使用相同程序进行分析。

结果

共有 55 个中心对调查做出了回应;其中 21 个使用导丝定位,其余 34 个中心使用不同的放射性外科手术技术(RGS)定位不可触及的乳腺病变,结果分为 13 个部分。ROLL 技术常用的示踪剂剂量为 111MBq,SNOLL 技术为 222MBq,示踪剂体积为 0.2ml。最常用的方案是 2 天方案。进行 CRG 的中心中有 26%使用 I 种子进行乳腺病变和可疑/病理性淋巴结的检测,植入和取出之间的时间约为 3 天,大多数情况下随后进行影像学检查。

结论

该调查显示了放射性外科手术在乳腺癌患者不同疾病阶段管理中的重要性,新技术和工具的应用存在差异,这与核医学服务的多种医疗保健现实情况相对应。

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