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家兔海马损伤与痕迹条件反射

Hippocampal lesions and trace conditioning in the rabbit.

作者信息

James G O, Hardiman M J, Yeo C H

出版信息

Behav Brain Res. 1987 Feb;23(2):109-16. doi: 10.1016/0166-4328(87)90048-9.

DOI:10.1016/0166-4328(87)90048-9
PMID:3566905
Abstract

Trace conditioning of the nictitating membrane response (NMR) was examined in rabbits with lesions of the dorsal hippocampus and fimbria-fornix. Using a white noise conditional stimulus and an electrical shock unconditional stimulus, the number and amplitude of conditional responses (CRs) was similar in hippocampus-lesioned and control subjects. At some stages of conditioning, the latencies of CRs from hippocampus-lesioned subjects were slightly shorter than those of the controls. We suggest that the hippocampus is not essential for trace conditioning but may exert a modulatory influence on the timing of the CR.

摘要

在患有背侧海马体和穹窿-海马伞损伤的兔子中,对瞬膜反应(NMR)的痕迹条件反射进行了研究。使用白噪声条件刺激和电击非条件刺激,海马体损伤组和对照组的条件反应(CRs)的数量和幅度相似。在条件反射的某些阶段,海马体损伤组的CRs潜伏期比对照组略短。我们认为,海马体对于痕迹条件反射并非必不可少,但可能对CR的时间安排施加调节性影响。

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1
Hippocampal lesions and trace conditioning in the rabbit.家兔海马损伤与痕迹条件反射
Behav Brain Res. 1987 Feb;23(2):109-16. doi: 10.1016/0166-4328(87)90048-9.
2
Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response.海马体与家兔经典条件反射性瞬膜反应的痕迹条件作用
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Retardation of rabbit nictitating membrane conditioning by subseizure electrical stimulation of hippocampus.海马亚惊厥电刺激对兔瞬膜条件反射的抑制作用。
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Hippocampectomy disrupts trace eye-blink conditioning in rabbits.海马切除术会破坏兔子的痕迹性眨眼条件反射。
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Classical conditioning of the nictitating membrane response of the rabbit. IV. Lesions of the inferior olive.家兔瞬膜反应的经典条件反射。IV. 下橄榄核损伤
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Hippocampal lesions disrupt classical conditioning of cross-modality reversal learning of the rabbit nictitating membrane response.海马体损伤会破坏兔子瞬膜反应的跨模态逆向学习的经典条件反射。
Behav Brain Res. 1986 Oct;22(1):85-9. doi: 10.1016/0166-4328(86)90083-5.

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