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肝移植术后鼻眶毛霉菌病,病情恶化的意外原因。

Postliver Transplantation Rhino-Orbital Mucormycosis, an Unexpected Cause of a Downhill Course.

作者信息

Sabhapandit Swapnali, Sharma Mithun, Sekaran Anuradha, Menon Balachandran, Kulkarni Anand, Tr Soumya, Nagaraja Rao Padaki, Nageshwar Reddy Duvurr

机构信息

Department of Ophthalmology, AIG Hospitals, Hyderabad, India.

Department of Hepatology and Liver Transplantation, Asian Institute of Gastroenterology, Hyderabad, India.

出版信息

Case Reports Hepatol. 2022 May 28;2022:5413315. doi: 10.1155/2022/5413315. eCollection 2022.

DOI:10.1155/2022/5413315
PMID:35669159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9167135/
Abstract

The COVID-19 pandemic has impacted transplantation worldwide in a major way with infections and post-COVID-19 complications contributing to increased mortality and morbidity. We present a case of a 42-year-old lady who developed rhino-orbital mucormycosis in a postliver transplantation period. The initial presentation of the patient was very subtle. She never had overt COVID-19 infection before surgery and in the recovery period. Though cases of mucormycosis in the wound site have been reported, this would be one of the rare cases of rhino-orbital mucormycosis postliver transplantation. This infection leads to a rapid downhill course and the death of the patient. Atypical infections and presentations need to be monitored in postliver transplantation patients who are getting operated on during this pandemic, and a high level of clinical suspicion is required to pick up these cases at an early stage.

摘要

新冠疫情对全球移植领域产生了重大影响,感染及新冠后遗症导致死亡率和发病率上升。我们报告一例42岁女性患者,在肝移植术后发生了鼻眶毛霉菌病。患者的初始表现非常隐匿。术前及恢复期她从未有过明显的新冠感染。虽然伤口部位毛霉菌病的病例已有报道,但这是肝移植术后罕见的鼻眶毛霉菌病病例之一。这种感染会导致病情迅速恶化,最终患者死亡。对于在此次疫情期间接受手术的肝移植术后患者,需要监测非典型感染和表现,并且需要高度的临床怀疑才能在早期发现这些病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dd1/9167135/d7bc72a29874/CRIHEP2022-5413315.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dd1/9167135/d7bc72a29874/CRIHEP2022-5413315.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dd1/9167135/d7bc72a29874/CRIHEP2022-5413315.001.jpg

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Coronavirus Disease, Diabetes and Glucocorticoid a Terrible Trio for Invasive Mucormycosis: An Observational Study from Northwest Rajasthan.
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