Department of Thoracic Surgery, Vanderbilt University Medical Center, 1161 21st Avenue South, D-4311 MCN, Nashville, TN 37232, USA.
Department of Thoracic Surgery, Vanderbilt University Medical Center, 609 Oxford House, 1313 21st Avenue South, Nashville, TN 37232, USA.
Surg Clin North Am. 2022 Jun;102(3):483-492. doi: 10.1016/j.suc.2022.01.006.
Current guidelines for non-small cell lung cancer (NSCLC) recommend segmentectomy over lobectomy for patients with poor pulmonary reserve or for peripheral nodules less than or equal to 2 cm with adenocarcinoma in situ histology, greater than 50% ground-glass opacity on computed tomography, or radiologic doubling time greater than or equal to 400 days. However, emerging data suggest oncologic equivalence of segmentectomy to lobectomy for less than or equal to 2 cm, peripheral stage IA NSCLC regardless of histologic type or radiographic findings.
目前的非小细胞肺癌(NSCLC)指南建议对于肺储备功能差的患者或具有原位腺癌组织学、在 CT 上具有大于 50%磨玻璃密度、或影像学倍增时间大于或等于 400 天的小于或等于 2cm 外周结节的患者,采用肺段切除术而非肺叶切除术。然而,新出现的数据表明,对于小于或等于 2cm、外周 I 期 NSCLC 的患者,无论组织学类型或影像学表现如何,肺段切除术与肺叶切除术在肿瘤学方面是等效的。