找到你的利基：静止肿瘤库中的免疫逃逸。
Finding your niche: immune evasion in quiescent tumor reservoirs.
机构信息
Division of Biological Sciences, University of California, San Diego, CA 92093, USA.
Division of Biological Sciences, University of California, San Diego, CA 92093, USA.
出版信息
Trends Immunol. 2022 Jul;43(7):500-502. doi: 10.1016/j.it.2022.05.003. Epub 2022 Jun 5.
Abstract
Emerging immunotherapies offer a new hope for cancer patients but are not always effective even when a tumor is recognized by the immune system. Baldominos and colleagues address this challenge by characterizing a resilient niche of metabolically unique quiescent cancer cells (QCCs) that resist T cell-mediated control.
摘要
新兴的免疫疗法为癌症患者带来了新的希望，但即使肿瘤被免疫系统识别，这些疗法也并不总是有效。Baldominos 及其同事通过描述代谢上独特的静止癌细胞（QCC）的弹性小生境来应对这一挑战，这些 QCC 能够抵抗 T 细胞介导的控制。
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本文引用的文献
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