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配对样本设计中比例差异检验的样本量。

Sample size for testing differences in proportions for the paired-sample design.

作者信息

Connor R J

出版信息

Biometrics. 1987 Mar;43(1):207-11.

PMID:3567305
Abstract

Miettinen (1968, Biometrics 24, 339-352) presented an approximation for power and sample size for testing the differences between proportions in the matched-pair case. Duffy (1984, Biometrics 40, 1005-1015) gave the exact power for this case and showed that Miettinen's approximation tends to slightly overestimate the power or underestimate the sample size necessary for the design power. A simple alternative approximation that is more conservative is presented here. In many cases, the sample size for the independent-sample case provides a conservative approximation for the matched-pair design.

摘要

米耶蒂宁(1968年,《生物统计学》第24卷,第339 - 352页)提出了一种用于检验配对情况下比例差异的功效和样本量的近似方法。达菲(1984年,《生物统计学》第40卷,第1005 - 1015页)给出了这种情况下的确切功效,并表明米耶蒂宁的近似方法往往会略微高估功效或低估达到设计功效所需的样本量。这里提出一种更保守的简单替代近似方法。在许多情况下,独立样本情况下的样本量为配对设计提供了一个保守的近似值。

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