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化脓性肝脓肿的特征:阿曼单中心经验。

Characteristics of Pyogenic Liver Abscess: Experience of a single centre in Oman.

机构信息

Department of Medicine, Royal Hospital, Muscat, Oman.

Department of Medicine, Ibri Hospital, Ibri, Oman.

出版信息

Sultan Qaboos Univ Med J. 2022 May;22(2):257-261. doi: 10.18295/squmj.5.2021.105. Epub 2022 May 26.

DOI:10.18295/squmj.5.2021.105
PMID:35673289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9155044/
Abstract

OBJECTIVES

This study aimed to analyse the epidemiological, aetiological and clinical characteristics of pyogenic liver abscess (PLA) occurring in Oman. The intention was to obtain the information needed for the adequate liver abscess (LA) empirical treatment. LA can develop as a complication of hepatobiliary disease or other intraabdominal infections, but more recently, it is associated with primary and secondary liver malignancies and their treatment.

METHODS

This retrospective study took place in the Royal Hospital, Muscat, Oman. Consecutive patients treated for LA from January 2013 to December 2017 were enrolled. Their demographic and clinical data were used to study the characteristics of PLA occurring in Oman.

RESULTS

A total of 53 patients with PLA were enrolled in the study. They were predominantly male and younger than 60 years. was found to be the most common bacteria causing LA. Clinical presentation was non-specific, and abdominal pain and high fever were the most common symptoms.

CONCLUSION

The majority of PLAs are caused by , so the empirical treatment should begin with antibiotic directed against it. Further studies are needed to establish the local role of anaerobic bacteria in PLA and monitor the presence of hypervirulent in Oman.

摘要

目的

本研究旨在分析在阿曼发生的化脓性肝脓肿(PLA)的流行病学、病因学和临床特征。目的是获得适当的肝脓肿(LA)经验性治疗所需的信息。LA 可作为肝胆疾病或其他腹腔内感染的并发症发生,但最近与原发性和继发性肝恶性肿瘤及其治疗有关。

方法

这项回顾性研究在阿曼的皇家医院进行。纳入了 2013 年 1 月至 2017 年 12 月期间因 LA 接受治疗的连续患者。使用他们的人口统计学和临床数据来研究在阿曼发生的 PLA 的特征。

结果

共有 53 名 PLA 患者入组本研究。他们主要是男性且年龄小于 60 岁。被发现是导致 LA 的最常见细菌。临床表现不具特异性,腹痛和高热是最常见的症状。

结论

大多数 PLA 由引起,因此经验性治疗应从针对它的抗生素开始。需要进一步的研究来确定厌氧菌在 PLA 中的本地作用,并监测高毒力在阿曼的存在。

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Pyogenic liver abscess: Clinical features and microbiological profiles in tertiary care center.化脓性肝脓肿:三级医疗中心的临床特征及微生物学特征
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Hypervirulent Klebsiella pneumoniae in Cryptogenic Liver Abscesses, Paris, France.法国巴黎,不明原因肝脓肿中产超毒力肺炎克雷伯菌。
Emerg Infect Dis. 2018 Feb;24(2):221-229. doi: 10.3201/eid2402.170957.
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Klebsiella Pneumoniae Liver Abscess: A Case Series of Six Asian Patients.肺炎克雷伯菌肝脓肿:6例亚洲患者的病例系列
Am J Case Rep. 2017 Sep 26;18:1028-1033. doi: 10.12659/ajcr.905191.
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Clinical and microbiological characteristics of pyogenic liver abscess in a tertiary hospital in East China.中国东部一家三级医院化脓性肝脓肿的临床及微生物学特征
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