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[人类1号、9号和16号染色体有丝分裂凝聚过程中C区段大小与相应常染色质区域的关系]

[Relation between the size of C-segments and corresponding euchromatic regions of human chromosomes 1, 9 and 16 during their mitotic condensation].

作者信息

Akopian G R, Sozanskiĭ O A, Guleiuk N L

出版信息

Biull Eksp Biol Med. 1987 Apr;103(4):454-6.

PMID:3567341
Abstract

The nature of associations between the length of C-segments and the corresponding euchromatic regions of chromosomes 1, 9, and 16 in the process of their mitotic condensation has been studied. Their statistically significant linear nature in the range of chromosome 2 condensation from 11 to 4 micron has been established. Within the interval of 6.5-8.5 micron the above association is less significant, at the same time minimal variability of C-segment length is observed as compared to other stages of mitotic condensation. It is recommended to define the absolute size of C-segments in chromosomes 1, 9 and 16 by measuring their dimensions in metaphase plates with chromosome 2 length from 6.5 to 8.5 micron. The regressional correction of the results of C-segment measurements or approximation of values depending on the statistical significance of linear regression equation coefficient has been demonstrated.

摘要

研究了在有丝分裂凝聚过程中,C段长度与1号、9号和16号染色体相应常染色质区域之间的关联性质。已确定在染色体2凝聚从11微米到4微米的范围内,它们具有统计学上显著的线性性质。在6.5 - 8.5微米的区间内,上述关联不太显著,同时与有丝分裂凝聚的其他阶段相比,观察到C段长度的变异性最小。建议通过在染色体2长度为6.5至8.5微米的中期板中测量1号、9号和16号染色体中C段的尺寸来确定其绝对大小。已证明根据线性回归方程系数的统计显著性对C段测量结果进行回归校正或对数值进行近似。

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