Garcia Karyne C, Confortin Susana C, Meneghini Vandrize, d'Orsi Eleonora, Barbosa Aline Rodrigues
Postgraduate Program in Physical Education, Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC Brazil.
Center for Biological and Health Sciences, Universidade Federal do Maranhão (UFMA), São Luís, MA Brazil.
J Diabetes Metab Disord. 2022 Jan 27;21(1):77-84. doi: 10.1007/s40200-021-00937-6. eCollection 2022 Jun.
To estimate the prevalence of Metabolic Syndrome (MetS) and its association with changes in modifiable risk factors in older adults from southern Brazil.
A longitudinal study was performed with data from EpiFloripa Aging study. We defined MetS by the existence of three or more of the following risk factors for cardiovascular disease (CVD): waist circumference (WC) (≥ 92 cm in men and ≥ 87 cm in women); fasting glucose (≥100 mg/dl); decreased HDL cholesterol (<40 mg/dl in men and <50 mg/dl in women); hypertriglyceridemia (≥150 mg/dl) and blood pressure (≥130/85 mmHg). We evaluated the changes in modifiable risk factors (smoking, alcohol consumption, fruit and vegetable consumption, physical activity, and body mass index) between the two moments of the study (2009/10 and 2013/14). Directed acyclic graph and logistic regression models were used.
Among the 599 participants, the prevalence of MetS was 64.0% (95% CI, 58.7-68.9). In the adjusted analysis, those who remained or became persons who are overweight (OR = 4.59; 95% CI: 3.05-6.89) and those who remained or became insufficiently active (OR = 1.92; 95% CI: 1.23-2.98) were more likely to present MetS.
Our findings suggest that being or becoming overweight and being or becoming insufficiently active are modifiable factors associated with MetS. These results highlight the need for developing preventive strategies for the observed risk indicators to mitigate the prevalence of MetS in older adults.
评估巴西南部老年人代谢综合征（MetS）的患病率及其与可改变风险因素变化的关联。
采用EpiFloripa衰老研究的数据进行纵向研究。我们根据存在以下三种或更多心血管疾病（CVD）风险因素来定义MetS：腰围（WC）（男性≥92厘米，女性≥87厘米）；空腹血糖（≥100毫克/分升）；高密度脂蛋白胆固醇降低（男性<40毫克/分升，女性<50毫克/分升）；高甘油三酯血症（≥150毫克/分升）和血压（≥130/85毫米汞柱）。我们评估了研究的两个时间点（2009/10年和2013/14年）之间可改变风险因素（吸烟、饮酒、水果和蔬菜摄入量、身体活动以及体重指数）的变化。使用了有向无环图和逻辑回归模型。
在599名参与者中，MetS的患病率为64.0%（95%置信区间，58.7 - 68.9）。在调整分析中，那些保持或变为超重的人（比值比[OR]=4.59；95%置信区间：3.05 - 6.89）以及那些保持或变为身体活动不足的人（OR = 1.92；95%置信区间：1.23 - 2.98）更有可能患MetS。
我们的研究结果表明，超重或变得超重以及身体活动不足或变得不足是与MetS相关的可改变因素。这些结果凸显了针对观察到的风险指标制定预防策略以降低老年人MetS患病率的必要性。
