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老年人代谢综合征及其相关因素:2015 年 SABE 哥伦比亚的二次分析。

Metabolic Syndrome and Its Associated Factors in Older Adults: A Secondary Analysis of SABE Colombia in 2015.

机构信息

Faculty of Education and Sport Sciences, University of Granada, Melilla, Spain.

Hospital Universitario San Ignacio-Aging Institute, Pontificia Universidad Javeriana, Bogotá, Colombia.

出版信息

Metab Syndr Relat Disord. 2020 Oct;18(8):389-398. doi: 10.1089/met.2019.0066. Epub 2020 Jun 29.

DOI:10.1089/met.2019.0066
PMID:32609058
Abstract

Understanding the metabolic syndrome (MetS) prevalence at the national level is important to develop effective programs and strategies to prevent and control MetS. This study aimed to analyze the prevalence of MetS according to gender and aging stage, and its association with potential factors in older individuals ≥60 years of age in Colombia. The data for this study came from a secondary cross-sectional, nationally representative SABE study Survey on Health, Well-Being, and Aging in Colombia, 2015. A total of 1637 participants (60.7% women, 70.5 ± 7.9 years) from 86 Colombian municipalities participated. A structured questionnaire was used to collect data on socio-demography, lifestyle, and self-report medical conditions. Measurements included anthropometric (weight, waist circumference, body mass index), sarcopenia "proxy" status (calf circumference) handgrip strength levels, high-density lipoprotein cholesterol, triglycerides, fasting glucose, and blood pressure. Univariate and multiple regression models were established as part of the main analysis. Using the harmonized Joint Scientific Statement criteria, MetS was present in 54.9% of the study population, with a higher prevalence among females than males (59.8% vs. 47.3%). Individuals who were cigarette smokers (odds ratio [OR] = 1.5; 95% confidence interval [CI] = 1.0-2.4;  = 0.034), female gender (OR = 1.3; 95% CI = 1.0-1.8;  = 0.020), and sarcopenia "proxy" (OR = 1.6; 95% CI = 1.0-2.5;  = 0.026) were more likely to have a higher prevalence estimate of MetS, after controlling for relevant covariates. Overall prevalence of MetS among older adults in Colombia is high. Smoking, female gender, and sarcopenia "proxy" status are associated with MetS. These results suggested that MetS is still a serious public burden in Colombia, and screening for promotion of healthy lifestyle and nutrition counseling should be offered routinely in old age.

摘要

了解国家层面代谢综合征(MetS)的患病率对于制定预防和控制 MetS 的有效计划和策略非常重要。本研究旨在根据性别和老龄化阶段分析 MetS 的患病率,并分析其与哥伦比亚 60 岁以上老年人潜在因素的关系。本研究的数据来自于一项二次横断面、全国代表性的 SABE 研究——哥伦比亚健康、幸福和老龄化调查,2015 年。共有 1637 名参与者(60.7%为女性,70.5±7.9 岁)来自 86 个哥伦比亚城市。使用结构化问卷收集社会人口统计学、生活方式和自我报告的医疗条件数据。测量包括人体测量学(体重、腰围、体重指数)、肌肉减少症“代理”状态(小腿围)握力水平、高密度脂蛋白胆固醇、甘油三酯、空腹血糖和血压。作为主要分析的一部分,建立了单变量和多变量回归模型。使用协调的联合科学声明标准,研究人群中有 54.9%患有 MetS,女性患病率高于男性(59.8%比 47.3%)。吸烟(比值比 [OR] = 1.5;95%置信区间 [CI] = 1.0-2.4; = 0.034)、女性性别(OR = 1.3;95% CI = 1.0-1.8; = 0.020)和肌肉减少症“代理”(OR = 1.6;95% CI = 1.0-2.5; = 0.026)的个体更有可能患有 MetS,在控制了相关协变量后。哥伦比亚老年人中 MetS 的总体患病率较高。吸烟、女性性别和肌肉减少症“代理”状态与 MetS 相关。这些结果表明,MetS 仍然是哥伦比亚的一个严重公共负担,应在老年期常规进行 MetS 筛查,以促进健康的生活方式和营养咨询。

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