Esmaeili Shahnaz, Bandarian Fatemeh, Gharishvandi Fatemeh, Razi Farideh, Hosseinkhani Shaghayegh, Namazi Nazli, Esmaeili Behnaz, Sanjari Mahnaz, Tootee Ali, Saeedi Saeedeh, Rambod Camelia, Aalaa Maryam, Fahimfar Noushin, Larijani Bagher, Nasli-Esfahani Ensieh
Diabetes Research Center, Endocrinology and Metabolism Clinical sciences Institute, Tehran University of Medical Sciences, PO Box: 1411413137, Tehran, Iran.
Personalized medicine research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
J Diabetes Metab Disord. 2022 May 25;21(1):1139-1148. doi: 10.1007/s40200-022-01037-9. eCollection 2022 Jun.
Mapping the available evidence can be used to inform current diabetes research, identify relevant gaps, and prioritize future research. In this regard, we mapped diabetes research performed in Iran.
We searched the Scopus and PubMed databases from 01/01/2015 till 01/01/2020 using keywords such as diabetes and Iran. The included articles were classified according to their document types, level of evidence, and subject areas.
The majority of the included articles (53%) were related to diabetes types, followed by complications (28%). Most of the documents were original articles (82%), and reviews were 18% of the publications. Systematic reviews constitute only 6% of the total documents. Observational studies were the most common types of study designs (26%), followed by clinical trials (20%). Moreover, topics on control and management of diabetes were the most prevalent subject areas (58%), and fewer studies were on preventive strategies (6%). In diabetes management studies, less attention has been paid to evaluate psychological (10%), educational (9%), and physical activity-related (7%) interventions. There was a shortage of secondary studies related to physical activity, psychology, diagnostic, and screening-related studies.
To fill diabetes research gaps, more investment in cost-effectiveness interventions, such as preventive strategies and behavioral self-management programs, need. Moreover, we need to pay more attention on applied sciences and real world evidence to bridge translational gaps from bench to bedside. In this regard, further data synthesis can be helpful in evaluating the effectiveness of the available studies and avoiding unnecessary investigations.
梳理现有证据可用于为当前糖尿病研究提供信息、识别相关差距并确定未来研究的优先事项。在这方面,我们梳理了伊朗开展的糖尿病研究。
我们使用“糖尿病”和“伊朗”等关键词,在2015年1月1日至2020年1月1日期间检索了Scopus和PubMed数据库。纳入的文章根据其文献类型、证据水平和主题领域进行分类。
纳入的文章中,大多数(53%)与糖尿病类型相关,其次是并发症(28%)。大多数文献为原创文章(82%),综述占出版物的18%。系统综述仅占文献总数的6%。观察性研究是最常见的研究设计类型(26%),其次是临床试验(20%)。此外,糖尿病控制和管理方面的主题是最普遍的主题领域(58%),关于预防策略的研究较少(6%)。在糖尿病管理研究中,对心理干预(10%)、教育干预(9%)和体育活动相关干预(7%)的评估关注较少。缺乏与体育活动、心理学、诊断和筛查相关的二次研究。
为填补糖尿病研究差距,需要对成本效益干预措施,如预防策略和行为自我管理项目,进行更多投资。此外,我们需要更加关注应用科学和真实世界证据,以弥合从实验室到临床的转化差距。在这方面,进一步的数据综合有助于评估现有研究的有效性并避免不必要的调查。