Kiwan Ruba, Son Maksim, Mayich Michael, Boulton Melfort, Pandey Sachin, Sharma Manas
Department of Medical Imaging, Northern Ontario School of Medicine, Sudbury.
Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
Surg Neurol Int. 2022 May 6;13:185. doi: 10.25259/SNI_69_2022. eCollection 2022.
Ruptured intracranial infected aneurysms (IIAs) are relatively rare, but they portend high mortality. To the best of our knowledge, there is no Canadian case series on IIA, as well there is a relative paucity of international published experiences. Our purpose is to share the experience of a single Canadian tertiary center in managing ruptured IIA and to conduct a systematic review.
We did a retrospective case review series of adult patients with ruptured IIA treated at our institution. Second, we conducted a systematic review of the literature on ruptured IIA between 2011 and 2021 inclusive.
At our institution, of a total eight cases with ruptured IIA, four were treated endovascularly and two by surgical bypass. For the systematic review, we included nine noncomparative studies with a total of 509 patients (318 males) and at least 437 ruptured IIA aneurysms. Favorable outcome was specified for 63.3% of patients ( = 57). Regarding ruptured IIA, favorable clinical outcome was described in 59.3% ( = 16).
This study highlights a single Canadian tertiary center experience in the management of IIA and compares it to the global trends of the past 10 years in a systematic review.
颅内感染性动脉瘤破裂（IIA）相对少见，但死亡率很高。据我们所知，加拿大尚无关于IIA的病例系列报道，国际上发表的相关经验也相对较少。我们的目的是分享一家加拿大三级医疗中心处理破裂IIA的经验并进行系统评价。
我们对在本机构接受治疗的成年破裂IIA患者进行了回顾性病例系列研究。其次，我们对2011年至2021年（含）期间关于破裂IIA的文献进行了系统评价。
在我们机构，8例破裂IIA患者中，4例接受了血管内治疗，2例接受了外科搭桥手术。在系统评价中，我们纳入了9项非对照研究，共509例患者（318例男性）和至少437个破裂的IIA动脉瘤。63.3%的患者（n = 57）获得了良好结局。关于破裂IIA，59.3%（n = 16）的患者获得了良好的临床结局。
本研究突出了一家加拿大三级医疗中心处理IIA的经验，并在系统评价中将其与过去10年的全球趋势进行了比较。
