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2 只圈养阿拉斯加驼鹿的软组织肉瘤。

Soft tissue sarcomas in 2 zoo-housed Alaskan moose.

机构信息

Michigan State University, College of Veterinary Medicine, East Lansing, MI, USA.

Potter Park Zoo, Lansing, MI, USA.

出版信息

J Vet Diagn Invest. 2022 Jul;34(4):662-667. doi: 10.1177/10406387221101853. Epub 2022 Jun 7.

Abstract

Soft tissue sarcomas (STSs) are common well-described cutaneous neoplasms in many domestic species. Few cutaneous neoplasms have been reported in cervids, other than papilloma virus-induced benign cutaneous fibromas (BCFs). Two wild-caught Alaskan moose (), housed at different North American zoos, were both presented with lameness and a mass. The gross appearance of each mass varied greatly; case 1 had a distinct, exophytic, ulcerated mass near the right carpal joint similar in appearance to a BCF, and case 2 had a pronounced swelling over the left hip. Based on histologic evaluation, both masses were diagnosed as STS. The clinical presentation of these masses included rapid growth and associated lameness; however, gross appearance was markedly different. Histopathology revealed characteristics typical of STS in other species, including spindle-shaped cells arranged in streaming sheets with ovoid nuclei. STS should be included as a differential diagnosis for moose with a cutaneous or subcutaneous soft tissue mass or swelling.

摘要

软组织肉瘤(STS)是许多常见家养动物中描述明确的皮肤肿瘤。除了由乳头瘤病毒引起的良性皮肤纤维瘤(BCF)外,鹿类中很少有皮肤肿瘤的报道。两只在野外捕获的阿拉斯加驼鹿(),分别饲养在北美两个不同的动物园,均出现跛行和肿块。每个肿块的大体外观差异很大;1 号病例在右腕关节附近有一个明显的外生性、溃疡性肿块,外观类似于 BCF,而 2 号病例在左臀部有明显肿胀。根据组织学评估,两个肿块均被诊断为 STS。这些肿块的临床表现包括快速生长和相关的跛行;然而,大体外观明显不同。组织病理学显示出与其他物种 STS 相似的特征,包括呈流线状排列的梭形细胞,具有卵圆形核。对于有皮肤或皮下软组织肿块或肿胀的驼鹿,应将 STS 作为鉴别诊断之一。

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