Suppr超能文献

经肝双腔血液透析导管在血管通路衰竭中的应用:血液透析患者的可行性、功能和结局。

Transhepatic double lumen hemodialysis catheter in exhausted vascular access: Feasibility, functionality, and outcome among hemodialysis patients.

机构信息

Department of Medicine, King Faisal Specialist Hospital and Research Center - Jeddah, Jeddah, Saudi Arabia.

Department of Medicine, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

J Vasc Access. 2024 Jan;25(1):165-171. doi: 10.1177/11297298221100456. Epub 2022 Jun 8.

Abstract

INTRODUCTION

Permanent arteriovenous fistula and graft are considered the best options for hemodialysis in end-stage renal disease patients. Temporary access using the internal jugular or femoral veins is the feasible option in acute cases of dialysis and if permanent access is unavailable. Occasionally, however, these access sites are unusable after consecutive blockage of the upper and lower extremities veins. A transhepatic or translumbar approach might be the only unconventional way to ensure a sufficient blood flow for adequate dialysis.

METHOD

Retrospective data on all transhepatic catheters (THCs) in patients at the King Faisal Specialist Hospital and Research Center in Jeddah, Saudi Arabia were collected. The catheters were inserted over a 10-year period (2009-2019). A minimum of 1 year of follow-up from the last catheter insertion was considered for analysis.

RESULTS

A total of 12 patients had THCs with a mean age of 42.5 ± 12.2 and pre-insertion mean dialysis duration of 130.0 ± 72.9 months. All catheters were functional from the start with no immediate complications. A total of 35 catheter replacements over guidewires were made with a median of 2.0 catheters (range of 0-10). The mean blood flow was 300 ± 30 ml/minute with a mean Kt/v of 1.4 ± 0.4. The median initial (primary) device service interval was 68 (range 6-1531 days) and the median total access site service interval was 392 (range 76-2698 days). Catheter complications included catheter migration, thrombosis, and bloodstream infection occurring at a rate of 0.12, 0.18, and 0.046 per 100 catheter days respectively.

CONCLUSIONS

Transhepatic catheters provide safe, feasible access in patients with exhausted vascular access. Patients who undergo THC insertion should be worked up for innovative permanent vascular access or urgent transplantation utilizing unconventional vascular techniques to avoid death due to lack of access.

摘要

简介

永久性动静脉瘘和移植物被认为是终末期肾病患者血液透析的最佳选择。在急性透析病例中,如果永久性通路不可用,使用颈内静脉或股静脉的临时通路是可行的选择。然而,偶尔这些通路在上下肢静脉连续阻塞后无法使用。经肝或经腰椎途径可能是确保足够血流量以进行充分透析的唯一非常规方法。

方法

收集沙特阿拉伯吉达的法伊萨尔国王专科医院和研究中心所有经肝导管(THC)患者的回顾性数据。这些导管在 10 年内(2009-2019 年)插入。从最后一次插入导管开始至少随访 1 年进行分析。

结果

共有 12 名患者接受了 THC,平均年龄为 42.5±12.2 岁,插入前平均透析时间为 130.0±72.9 个月。所有导管从一开始就具有功能,没有立即出现并发症。总共进行了 35 次经导丝更换导管,中位数为 2.0 个导管(范围 0-10)。平均血流量为 300±30ml/分钟,平均 Kt/v 为 1.4±0.4。初始(主要)设备服务间隔的中位数为 68(范围 6-1531 天),总通路服务间隔的中位数为 392(范围 76-2698 天)。导管并发症包括导管迁移、血栓形成和血流感染,发生率分别为 0.12、0.18 和 0.046/100 导管天。

结论

经肝导管为血管通路用尽的患者提供了安全可行的通路。接受 THC 插入术的患者应接受创新的永久性血管通路或紧急移植的评估,利用非常规血管技术,以避免因缺乏通路而导致死亡。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验