Hospital Unimed Volta Redonda , Departamento de Doenças Infecciosas , Volta Redonda , Rio de Janeiro , Brazil.
Hospital Unimed Volta Redonda , Laboratório de Microbiologia , Volta Redonda , Rio de Janeiro , Brazil.
Rev Inst Med Trop Sao Paulo. 2022 Jun 6;64:e36. doi: 10.1590/S1678-9946202264036. eCollection 2022.
Burkholderia cepacia complex (BCC) is group of widespread gram-negative bacillus organized in over 20 phylogenetically distinct bacterial species. According to previous studies, BCC species pathogens are widely reported in patients with cystic fibrosis (CF), but not in individuals with diabetes mellitus (DM). In this case report, a 42-year-old male patient with DM and a foot infection caused by BCC is presented. The patient was hospitalized after antibiotic treatment failure and improved after two surgical debridement procedures and a high-dose extended infusion (EI) of meropenem. The team of vascular surgeons and the infectious disease specialists worked fervently to solve the case. Finally, a scoping review was conducted to map BCC infections in patients with DM.
洋葱伯克霍尔德菌复合体（BCC）是一组广泛存在的革兰氏阴性杆菌，由 20 多种在系统发育上不同的细菌组成。根据之前的研究，BCC 种病原菌在囊性纤维化（CF）患者中广泛报道，但在糖尿病患者（DM）中不常见。在本病例报告中，介绍了一名 42 岁的男性 DM 患者，他患有由 BCC 引起的足部感染。该患者在抗生素治疗失败后住院，并在两次手术清创和大剂量延长输注（EI）美罗培南治疗后得到改善。血管外科医生团队和传染病专家团队努力解决了这个病例。最后，进行了范围综述，以绘制糖尿病患者 BCC 感染图谱。
