Martin D F, Tweedle D E
Br J Surg. 1987 Mar;74(3):209-11. doi: 10.1002/bjs.1800740320.
Endoscopic sphincterotomy was attempted in 81 patients with gallbladders for the primary management of symptomatic common duct stones and was successful in 80. Immediate complications occurred in six (7 per cent) and one patient died (1 per cent). Clearance of the common duct was achieved in 70 (86 per cent). Eight patients required surgery for failed clearance of the duct and suffered no operative mortality. Of 70 patients with cleared ducts, 5 underwent elective cholecystectomy. Four other patients with persistent or recurrent symptoms have required cholecystectomy, also without mortality. Sixty-one patients were reviewed 12-44 months (mean 24; median 22 months) after endoscopic sphincterotomy. Eighteen have died, none from biliary disease. Forty-three patients remain alive and well, free of biliary symptoms since, endoscopic sphincterotomy. When the surgical risk of cholecystectomy and choledocholithotomy is high, endoscopic sphincterotomy is effective and safe. Routine cholecystectomy is not indicated when the common duct has been cleared.
对81例胆囊患者尝试进行内镜括约肌切开术,以作为有症状胆总管结石的主要治疗方法,80例手术成功。6例(7%)出现即刻并发症,1例患者死亡(1%)。70例(86%)实现了胆总管通畅。8例患者因胆管清除失败而需要手术,且无手术死亡病例。在70例胆管通畅的患者中,5例接受了择期胆囊切除术。另外4例有持续或复发症状的患者也需要进行胆囊切除术,同样无死亡病例。在内镜括约肌切开术后12 - 44个月(平均24个月;中位数22个月)对61例患者进行了复查。18例患者死亡,均非死于胆道疾病。43例患者仍然健在,自内镜括约肌切开术后无胆道症状。当胆囊切除术和胆总管切开取石术的手术风险较高时,内镜括约肌切开术有效且安全。当胆总管已通畅时,不建议进行常规胆囊切除术。