Department of Cardiology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.
Braz J Cardiovasc Surg. 2022 Dec 1;37(6):908-913. doi: 10.21470/1678-9741-2020-0443.
The relationship between mitral annular calcification (MAC) and the controlling nutritional status (CONUT) score has not been previously studied. In this study, we investigated the relationship between MAC and CONUT score to evaluate the nutritional status of patients with MAC.
A total of 275 patients, including 150 patients with MAC and 125 patients without MAC, who presented to a cardiology outpatient clinic were enrolled in the study.
There was no difference in the CONUT score between the two groups. Correlation analysis indicated that CONUT score was positively correlated with left atrial (LA) diameter (r=0.190, P=0.020) and interventricular septum thickness (r=0.179, P=0.028) in the MAC+ group. In multivariate regression analysis, only LA diameter (odds ratio 95% confidence interval = 1,054-1,189, P=0.0001) was independently associated with MAC.
The present study investigated the relationship between CONUT score and MAC for the first time in the literature. We demonstrated that CONUT score was not significantly higher in patients with MAC without chronic diseases. However, CONUT score was correlated with LA diameter in patients with MAC. We therefore conclude that, for patients admitted with MAC and high LA diameter, CONUT is a valuable nutritional and inflammatory status index.
二尖瓣环钙化（MAC）与控制营养状况（CONUT）评分之间的关系尚未被研究过。在这项研究中，我们研究了 MAC 与 CONUT 评分之间的关系，以评估患有 MAC 的患者的营养状况。
共纳入 275 名患者，包括 150 名 MAC 患者和 125 名无 MAC 患者，这些患者均在心血管内科门诊就诊。
两组间 CONUT 评分无差异。相关性分析表明，在 MAC+组中，CONUT 评分与左心房（LA）直径（r=0.190，P=0.020）和室间隔厚度（r=0.179，P=0.028）呈正相关。在多变量回归分析中，只有 LA 直径（优势比 95%置信区间=1.054-1.189，P=0.0001）与 MAC 独立相关。
本研究首次在文献中研究了 CONUT 评分与 MAC 之间的关系。我们表明，在无慢性病的 MAC 患者中，CONUT 评分并没有显著升高。然而，CONUT 评分与 MAC 患者的 LA 直径相关。因此，我们得出结论，对于因 MAC 和高 LA 直径而住院的患者，CONUT 是一个有价值的营养和炎症状态指标。
