Mos J, Olivier B, Lammers J H, van der Poel A M, Kruk M R, Zethof T
Brain Res. 1987 Feb 24;404(1-2):263-6. doi: 10.1016/0006-8993(87)91377-1.
Female Wistar rats were tested for aggressive behaviour induced by electrical brain stimulation (EBS) in the lateral hypothalamus. Threshold currents for the induction of aggression were determined on several days before the females were paired with experienced breeder males. Beginning in the second week of pregnancy threshold current values were measured once or twice weekly. No change in thresholds was observed either during pregnancy, the early postpartum period or after weaning. Lactation was the only period during which the females were spontaneously aggressive towards male intruders in their home cage, but not in the EBS cage. Analysis of bite targets revealed no difference between the bite patterns in the postpartum maternal aggression test and the EBS-induced attacks. The results demonstrate that the change in physiological and hormonal status in pregnant and lactating females has no influence on the propensity to attack during EBS. The similarity in wound patterns does not advocate a major difference in the types of aggression studied. We speculate upon the nature of EBS-induced attacks as the activation of a rigid, final pathway of aggression which is rather insensitive to mild modulations.
对雌性Wistar大鼠进行了下丘脑外侧脑电刺激（EBS）诱导攻击行为的测试。在雌性大鼠与经验丰富的种公鼠配对前的几天，确定诱导攻击行为的阈电流。从怀孕第二周开始，每周测量一次或两次阈电流值。在怀孕期、产后早期或断奶后，均未观察到阈电流的变化。哺乳期是雌性大鼠在其饲养笼中对雄性入侵者自发产生攻击行为的唯一时期，但在EBS笼中则不会。对撕咬目标的分析表明，产后母性攻击测试中的撕咬模式与EBS诱导攻击之间没有差异。结果表明，怀孕和哺乳期雌性大鼠生理和激素状态的变化对EBS期间的攻击倾向没有影响。伤口模式的相似性并不表明所研究的攻击类型存在重大差异。我们推测EBS诱导攻击的本质是激活了一条僵化的、最终的攻击途径，该途径对轻微调节相当不敏感。
