From the Department of Anesthesia (Hilal), King Fahad General Hospital, and from the Department of Anesthesia and Critical Care (Alyamani, Kaki), Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Saudi Med J. 2022 Jun;43(6):551-558. doi: 10.15537/smj.2022.43.6.20220089.
To assess the effect of bupivacaine application following pulsed radiofrequency (PRF) ablation on trigeminal facial pain.
A total of 73 patients with trigeminal facial pain refractory to conservative therapy were randomized into 2 groups. Group I subjects underwent PRF ablation procedure, followed by the injection of 1 ml of bupivacaine. Whereas, Group II underwent the same procedure followed by the injection of 1 ml of normal saline. Pain relief duration, the time of onset of pain relief, and analgesic effect evaluated by numerical pain rating scale were considered as outcomes.
Thirty-nine patients in Group I and 34 in Group II. The duration of pain relief in the 2 groups was comparable (5 months in Group I vs. 6 months in Group II, =0.53). The onset of pain relief in the patients of Group I was shorter than Group II (0 days vs. 4.5 days, <0.001). The binary logistic regression analysis revealed that the application of bupivacaine alone had a significant effect on the reduction of the intake of medications (<0.05).
In situations involving patients who require rapid pain relief, bupivacaine injection following PRF ablation can be employed to provide immediate relief without subjecting the patients to the risks associated with major complications.
评估脉冲射频 (PRF) 消融后应用布比卡因对三叉神经面部疼痛的影响。
将 73 例对保守治疗无效的三叉神经面部疼痛患者随机分为 2 组。组 I 患者接受 PRF 消融术，然后注射 1ml 布比卡因。而组 II 患者接受相同的程序，然后注射 1ml 生理盐水。疼痛缓解持续时间、疼痛缓解开始时间和数字疼痛评分量表评估的镇痛效果被视为结果。
组 I 有 39 例患者，组 II 有 34 例患者。2 组的疼痛缓解持续时间相当（组 I 为 5 个月，组 II 为 6 个月，=0.53）。组 I 患者的疼痛缓解开始时间短于组 II（0 天 vs. 4.5 天，<0.001）。二元逻辑回归分析显示，单独应用布比卡因对减少药物摄入有显著影响（<0.05）。
在需要快速缓解疼痛的情况下，PRF 消融后应用布比卡因注射可以立即缓解疼痛，而不会使患者面临与主要并发症相关的风险。
