• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠新纹状体中多巴胺受体的马赛克样分布及其与纹状体小体的关系。

A mosaic-like distribution of dopamine receptors in rat neostriatum and its relationship to striosomes.

作者信息

Loopuijt L D, Sebens J B, Korf J

出版信息

Brain Res. 1987 Mar 10;405(2):405-8. doi: 10.1016/0006-8993(87)90315-5.

DOI:10.1016/0006-8993(87)90315-5
PMID:3567618
Abstract

The distribution of dopamine receptors in rat neostriatum was determined by means of light microscopic autoradiography of in vivo labeled binding sites for [3H]N-n-propylnorapomorphine and compared with the distribution of acetylcholinesterase histochemical staining. The distribution of dopamine receptors was non-homogeneous and patches of low receptor density were in register with acetylcholinesterase-poor striosomes. This suggests that the distribution pattern of dopamine receptors is specifically related to various input systems.

摘要

通过对体内[3H]N-正丙基去甲阿扑吗啡标记结合位点进行光学显微镜放射自显影,确定了大鼠新纹状体中多巴胺受体的分布,并与乙酰胆碱酯酶组织化学染色的分布进行了比较。多巴胺受体的分布不均匀,受体密度低的区域与乙酰胆碱酯酶含量少的纹状体小体相对应。这表明多巴胺受体的分布模式与各种输入系统存在特定关联。

相似文献

1
A mosaic-like distribution of dopamine receptors in rat neostriatum and its relationship to striosomes.大鼠新纹状体中多巴胺受体的马赛克样分布及其与纹状体小体的关系。
Brain Res. 1987 Mar 10;405(2):405-8. doi: 10.1016/0006-8993(87)90315-5.
2
Distribution of dopamine D-2 receptors in the rat striatal complex and its comparison with acetylcholinesterase.大鼠纹状体复合体中多巴胺D-2受体的分布及其与乙酰胆碱酯酶的比较。
Brain Res Bull. 1989 May;22(5):805-17. doi: 10.1016/0361-9230(89)90023-3.
3
Heterogeneous distribution of dopamine D2 receptors within the rat striatum as revealed by autoradiography of [3H]N-n-propylnorapomorphine binding sites.[3H]N-正丙基去甲阿朴吗啡结合位点的放射自显影显示大鼠纹状体内多巴胺D2受体的异质性分布。
Neurosci Lett. 1985 Jun 4;57(1):7-12. doi: 10.1016/0304-3940(85)90032-1.
4
Correspondence between the dopamine islands and striosomes of the mammalian striatum.哺乳动物纹状体中多巴胺岛与纹状体小体之间的对应关系。
Neuroscience. 1984 Dec;13(4):1157-87. doi: 10.1016/0306-4522(84)90293-8.
5
Compartment-specific changes in the density of choline and dopamine uptake sites and muscarinic and dopaminergic receptors during the development of the baboon striatum: a quantitative receptor autoradiographic study.狒狒纹状体发育过程中胆碱和多巴胺摄取位点以及毒蕈碱和多巴胺能受体密度的特定区域变化:定量受体放射自显影研究
J Comp Neurol. 1989 Oct 15;288(3):428-46. doi: 10.1002/cne.902880306.
6
Differential labelling of dopamine receptors in rat brain in vivo: comparison of [3H]piribedil, [3H]S 3608 and [3H]N,n-propylnorapomorphine.大鼠脑内多巴胺受体的体内差异标记:[3H]哌立地尔、[3H]S 3608和[3H]N,N-丙基去甲阿扑吗啡的比较
Eur J Pharmacol. 1983 Jan 28;87(1):85-94. doi: 10.1016/0014-2999(83)90053-5.
7
Synthesis and dopamine receptor affinity of (R)-(-)-2-fluoro-N-n-propylnorapomorphine: a highly potent and selective dopamine D2 agonist.
J Med Chem. 1990 Dec;33(12):3122-4. doi: 10.1021/jm00174a002.
8
Patterns of muscarinic cholinergic binding in the striatum and their relation to dopamine islands and striosomes.纹状体内毒蕈碱胆碱能结合模式及其与多巴胺岛和纹状体小体的关系。
J Comp Neurol. 1985 Jul 8;237(2):176-94. doi: 10.1002/cne.902370204.
9
Cholecystokinin peptides in vitro modulate the characteristics of the striatal 3H-N-propylnorapomorphine sites.胆囊收缩素肽在体外调节纹状体3H-N-丙基去甲阿朴吗啡位点的特性。
Acta Physiol Scand. 1983 May;118(1):79-81. doi: 10.1111/j.1748-1716.1983.tb07244.x.
10
Dopamine D1 receptor development in the rat striatum: early localization in striosomes.
Brain Res. 1989 Feb 20;480(1-2):170-7. doi: 10.1016/0006-8993(89)91579-5.

引用本文的文献

1
Neurochemical characterization of the tree shrew dorsal striatum.树鼩背侧纹状体的神经化学特征。
Front Neuroanat. 2011 Aug 17;5:53. doi: 10.3389/fnana.2011.00053. eCollection 2011.
2
Parallel changes in dopamine D2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine.边缘前脑多巴胺D2受体结合的平行变化与慢性轻度应激诱导的快感缺失及其被丙咪嗪逆转有关。
Psychopharmacology (Berl). 1994 Aug;115(4):441-6. doi: 10.1007/BF02245566.