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中脑导水管周围灰质尾部损伤会妨碍出血期间动脉血压的代偿。

Lesions of the caudal periaqueductal gray prevent compensation of arterial pressure during hemorrhage.

作者信息

Ward D G, Darlington D N

出版信息

Brain Res. 1987 Mar 31;407(2):369-75. doi: 10.1016/0006-8993(87)91116-4.

DOI:10.1016/0006-8993(87)91116-4
PMID:3567651
Abstract

Arterial pressure normally changes very little during small hemorrhage. In cats with bilateral lesions of the region of the caudal periaqueductal gray arterial pressure and renal vascular resistance decreased rapidly and precipitously during a 10 ml/kg X 3 min-1 hemorrhage. This lack of compensation was pronounced in response to a hemorrhage one week after lesioning but was not seen 1 h after lesioning in separate experiments. The critical region appears anterior and dorsal to the locus coeruleus and medial to the parabrachial nuclei.

摘要

在小量出血期间,动脉压通常变化很小。在双侧尾侧导水管周围灰质区域损伤的猫中,在以10毫升/千克×3分钟-1的速度出血期间,动脉压和肾血管阻力迅速且急剧下降。损伤后一周对出血的这种缺乏代偿的情况很明显,但在单独的实验中损伤后1小时未见此现象。关键区域似乎位于蓝斑前方和背侧以及臂旁核内侧。

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Lesions of the caudal periaqueductal gray prevent compensation of arterial pressure during hemorrhage.中脑导水管周围灰质尾部损伤会妨碍出血期间动脉血压的代偿。
Brain Res. 1987 Mar 31;407(2):369-75. doi: 10.1016/0006-8993(87)91116-4.
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