Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
World J Surg Oncol. 2022 Jun 8;20(1):188. doi: 10.1186/s12957-022-02651-w.
Peritonitis associated with fungal species Curvularia lunata seldom occurs with only five cases reported in the literature, all in middle-age patients with comorbidities undergoing dialysis.
A 21-year-old female who was referred to surgical oncology OPD with a diagnosis of ovarian malignancy, based on raised cancer antigen 125 (CA 125) and suspected tubo-ovarian mass (TOM) on magnetic resonance imaging (MRI). A review of the MRI showed a pelvic collection with TOM, suggestive of infective pathology. Fungal culture and mass spectroscopy of the cystic collection identified the presence of Curvularia lunata. She was treated with oral itraconazole which showed symptomatic improvement and radiological response. In the follow-up period, the patient developed chest wall swelling, aspiration and geneXpert® revealed multidrug-resistant (MDR) tuberculosis, and treatment was started.
Unusual causes of TOM and raised CA 125 should be kept in mind when dealing with young patients, as the possibility of epithelial ovarian cancer in this age is very low.
与真菌弯孢属相关的腹膜炎很少见，文献中仅报告了 5 例，均发生在患有合并症并接受透析的中年患者中。
一名 21 岁女性因卵巢恶性肿瘤被转至肿瘤外科门诊，基于升高的癌抗原 125（CA 125）和疑似输卵管卵巢肿块（TOM）的磁共振成像（MRI）。对 MRI 的回顾显示盆腔积液合并 TOM，提示感染性病变。囊肿积液的真菌培养和质谱分析鉴定出弯孢属的存在。她接受了伊曲康唑口服治疗，症状改善和影像学反应。在随访期间，患者出现胸壁肿胀、吸入，并通过基因 Xpert®检测出耐多药（MDR）结核，开始进行治疗。
在处理年轻患者时，应注意不常见的 TOM 和升高的 CA 125 原因，因为该年龄段上皮性卵巢癌的可能性非常低。
