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罗哌卡因与利多卡因在双眼皮整形术中的比较分析

Ropivacaine and Lidocaine in Double Eyelid Blepharoplasty: A Comparative Analysis.

作者信息

Liu Shaobo, Chu Zheng

机构信息

Department of Plastic Surgery, Pangang Group General Hospital, Panzhihua, Sichuan, China.

Department of Cosmetic Surgery, Xinjiang Plastic Surgery Hospital, Urumqi, China.

出版信息

Evid Based Complement Alternat Med. 2022 May 29;2022:7029570. doi: 10.1155/2022/7029570. eCollection 2022.

Abstract

Double eyelid blepharoplasty is an operation of changing the structure of the eyelid and reshaping the eyelid to form a new upper eyelid fold. This prospective randomized controlled study aimed to compare and evaluate the effect of ropivacaine and lidocaine in double eyelid blepharoplasty. A total of 120 patients who underwent double eyelid blepharoplasty in the beauty department of our hospital from January 2019 to July 2021 were enrolled and randomized (1 : 1) into the control group (1% lidocaine-epinephrine mixture) and the study group (0.75% ropivacaine-epinephrine mixture) via the random number table method. The 0.75% ropivacaine-epinephrine mixture led to lower Wong-Baker FACES Pain Rating visual analog scale score from 2 h to 1 d after surgery versus 1% lidocaine-epinephrine mixture (all < 0.05). The operation time, intraoperative anesthetic drug dosage, and intraoperative blood loss were similar in the two groups (all < 0.05). The 0.75% ropivacaine-epinephrine mixture resulted in a lower postoperative swelling score, but a higher patient satisfaction score versus 1% lidocaine-epinephrine mixture (all < 0.05). The safety profiles of the two groups were similar (all < 0.05). Both lidocaine and ropivacaine produce desirable anesthesia effects in double eyelid blepharoplasty. Ropivacaine can significantly reduce postoperative pain and mitigate postoperative swelling, with better satisfaction, and is thus worthy of further promotion.

摘要

双眼皮成形术是一种改变眼睑结构并重塑眼睑以形成新的上睑皱襞的手术。这项前瞻性随机对照研究旨在比较和评估罗哌卡因和利多卡因在双眼皮成形术中的效果。选取2019年1月至2021年7月在我院美容科接受双眼皮成形术的120例患者,通过随机数字表法将其随机(1∶1)分为对照组(1%利多卡因-肾上腺素混合液)和研究组(0.75%罗哌卡因-肾上腺素混合液)。与1%利多卡因-肾上腺素混合液相比,0.75%罗哌卡因-肾上腺素混合液在术后2小时至1天导致较低的Wong-Baker面部表情疼痛评分视觉模拟量表评分(均<0.05)。两组的手术时间、术中麻醉药物用量和术中出血量相似(均<0.05)。与1%利多卡因-肾上腺素混合液相比,0.75%罗哌卡因-肾上腺素混合液导致术后肿胀评分较低,但患者满意度评分较高(均<0.05)。两组的安全性相似(均<0.05)。利多卡因和罗哌卡因在双眼皮成形术中均产生理想的麻醉效果。罗哌卡因可显著减轻术后疼痛并减轻术后肿胀,满意度更高,因此值得进一步推广。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbac/9168085/2de86788d941/ECAM2022-7029570.001.jpg

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