[急性淋巴细胞白血病患儿的中性粒细胞功能]
[Neutrophil function in children with acute lyphoblastic leukemia].
作者信息
De Martino M, Guazzelli C, Biadaioli R, Cosenza E, Novembre E, Pisanu C, Vierucci A
出版信息
Ann Sclavo. 1977 Sep-Oct;19(5):1109-18.
Neutrophil function has been studied in 12 patients with acute lymphoblastic leukemia by means of the NBT test and bactericidal assay against E. coli. Tests have been performed before and during treatment. In untreated patients the bactericidal activity of neutrophils was normal, in spite of the decreased number of cells reducing the NBT dye after activation with immuno-complexes. In remission, those patients showed normal reduction. No correlation was observed between the bactericidal power registered after cranial irradiation and the NBT test.
通过硝基四氮唑蓝（NBT）试验和针对大肠杆菌的杀菌试验，对12例急性淋巴细胞白血病患者的中性粒细胞功能进行了研究。在治疗前和治疗期间均进行了测试。在未经治疗的患者中，尽管用免疫复合物激活后能使NBT染料还原的细胞数量减少，但中性粒细胞的杀菌活性正常。在缓解期，这些患者表现出正常的还原能力。未观察到颅脑照射后测得的杀菌能力与NBT试验之间存在相关性。
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