Defending the island against excess heme.
作者信息
Blanc Lionel, Lipton Jeffrey M
机构信息
1The Feinstein Institutes for Medical Research.
Cohen Children's Medical Center of New York.
出版信息
Blood. 2022 Jun 9;139(23):3359-3360. doi: 10.1182/blood.2022016341.
Abstract
摘要
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本文引用的文献
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Diamond-Blackfan anemia. Diamond-Blackfan 贫血。
Blood. 2020 Sep 10;136(11):1262-1273. doi: 10.1182/blood.2019000947.
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Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias.艾曲泊帕用于中度再生障碍性贫血或单系血细胞减少症患者。
Blood Adv. 2020 Apr 28;4(8):1700-1710. doi: 10.1182/bloodadvances.2020001657.
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Eltrombopag: a powerful chelator of cellular or extracellular iron(III) alone or combined with a second chelator.艾曲泊帕：一种单独或与第二种螯合剂联合使用的强效细胞内或细胞外铁（III）螯合剂。
Blood. 2017 Oct 26;130(17):1923-1933. doi: 10.1182/blood-2016-10-740241. Epub 2017 Sep 1.
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Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome.珠蛋白合成延迟导致血红素过量，进而引发钻石黑范贫血和5号染色体长臂缺失骨髓增生异常综合征的大细胞性贫血。
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Diamond Blackfan anemia: a model for the translational approach to understanding human disease. Diamond Blackfan 贫血：一种用于理解人类疾病的转化方法的模型。
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Ribosomopathies: human disorders of ribosome dysfunction.核糖体病：核糖体功能障碍的人类疾病。
Blood. 2010 Apr 22;115(16):3196-205. doi: 10.1182/blood-2009-10-178129. Epub 2010 Mar 1.
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The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia.编码核糖体蛋白S19的基因在先天性纯红细胞再生障碍性贫血中发生突变。
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