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[儿童肺含铁血黄素沉着症。免疫学研究]

[Pulmonary hemosiderosis in children. Immunologic study].

作者信息

Lévy M, Cayroche P, Chang A W, Reinert P

出版信息

Arch Fr Pediatr. 1978 Apr;35(4):382-94.

PMID:356798
Abstract

Circulating anti alveolar basement membrane antibodies have been detected by indirect immunofluorescence on lung rat in two out of five children presenting with pulmonary hemosiderosis. The two cases are reported and seem to be consistent with an auto-immune disease due to anti-basement membrane antibodies. Authors outline the presence of anti-reticulin antibodies in the two cases reported and the high level of IgE which seems a frequent finding in pulmonary hemosiderosis.

摘要

在五名患有肺含铁血黄素沉着症的儿童中,有两名通过对大鼠肺组织进行间接免疫荧光检测发现了循环抗肺泡基底膜抗体。现报告这两例病例,它们似乎符合由抗基底膜抗体引起的自身免疫性疾病。作者概述了所报告的两例病例中抗网状纤维抗体的存在情况以及在肺含铁血黄素沉着症中似乎常见的高水平免疫球蛋白E。

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