CINTESIS-Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal.
USF Esgueira +, 3800-322 Aveiro, Portugal.
Int J Environ Res Public Health. 2022 Jun 4;19(11):6896. doi: 10.3390/ijerph19116896.
Inappropriate prescribing, which encompasses the prescription of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), is a common problem for older people. The STOPP/START tool enables general practitioners, who are the main prescribers, to identify and reduce the incidence of PIMs and PPOs and appraise an older patient’s prescribed drugs during the diagnosis process to improve the clinical care quality. This study aimed to translate and validate the STOPP/START screening tool to enable its use by Portuguese physicians. A translation-back translation method including the validation of the obtained Portuguese version was used. Intra- and inter-rater reliability and agreement analyses were used in the validation process. A dataset containing the information of 334 patients was analyzed by one GP twice within a 2-week interval, while a dataset containing the information of 205 patients was independently analyzed by three GPs. Intra-rater reliability assessment led to a Kappa coefficient (κ) of 0.70 (0.65−0.74) for the STOPP criteria and 0.60 (0.52−0.68) for the START criteria, considered to be substantial and moderate values, respectively. The results of the inter-rater reliability rating were almost perfect for all combinations of raters (κ > 0.93). The version of the STOPP/START criteria translated into Portuguese represents an improvement in managing the medications prescribed to the elderly. It provides clinicians with a screening tool for detecting potentially inappropriate prescribing in patients older than 65 years old that is reliable and easy to use.
不适当的处方,包括潜在不适当药物的处方(PIMs)和潜在处方遗漏(PPOs),是老年人常见的问题。STOPP/START 工具使主要处方医生(全科医生)能够识别和减少潜在不适当药物和潜在处方遗漏的发生,并在诊断过程中评估老年患者的处方药物,以提高临床护理质量。本研究旨在翻译和验证 STOPP/START 筛选工具,使其可供葡萄牙医生使用。采用翻译-回译方法,包括对获得的葡萄牙语版本进行验证。在验证过程中使用了内部和外部评估者的可靠性和一致性分析。一个包含 334 名患者信息的数据集由一位全科医生在两周内两次进行分析,而一个包含 205 名患者信息的数据集由三位全科医生独立进行分析。内部评估者可靠性评估导致 STOPP 标准的 Kappa 系数(κ)为 0.70(0.65-0.74),START 标准的 Kappa 系数为 0.60(0.52-0.68),分别被认为是实质性和中等值。所有评估者组合的结果均为几乎完美(κ>0.93)。翻译成葡萄牙语的 STOPP/START 标准版本代表了管理 65 岁以上老年人处方药物的改进。它为临床医生提供了一种筛选工具,用于检测 65 岁以上患者潜在不适当的处方,该工具具有可靠性和易用性。