红细胞细胞研究：三维染色质、转录因子及其他。
Erythroid Cell Research: 3D Chromatin, Transcription Factors and Beyond.
机构信息
IGMM, Université Montpellier, CNRS, 34093 Montpellier, France.
Laboratory of Excellence GR-Ex, Université de Paris, 75015 Paris, France.
出版信息
Int J Mol Sci. 2022 May 30;23(11):6149. doi: 10.3390/ijms23116149.
Studies of the regulatory networks and signals controlling erythropoiesis have brought important insights in several research fields of biology and have been a rich source of discoveries with far-reaching implications beyond erythroid cells biology. The aim of this review is to highlight key recent discoveries and show how studies of erythroid cells bring forward novel concepts and refine current models related to genome and 3D chromatin organization, signaling and disease, with broad interest in life sciences.
对调控网络和信号控制红细胞生成的研究为生物学的几个研究领域带来了重要的见解，并且是发现远远超出红细胞生物学范围的深远意义的丰富来源。本文综述的目的是强调最近的关键发现，并展示红细胞研究如何提出与基因组和 3D 染色质组织、信号和疾病相关的新概念，并完善当前的模型，这些都在生命科学中引起了广泛的兴趣。
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