Lugo Merly Ambar N, Montalvo Toledo Lorena A, Requejo Guillermo A, Meléndez Alexander, Álvarez Samuel, López Andrés, Ríos Radames, Villegas Victor M, Oliver Armando L
Department of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR 00936, USA.
J Clin Med. 2022 Jun 1;11(11):3145. doi: 10.3390/jcm11113145.
Endophthalmitis treatment consists of intravitreal antibiotics injections and, in selected circumstances, pars plana vitrectomy. However, severe or refractory cases may require an enucleation or evisceration (ENEV). Our study seeks to identify risk factors leading to enucleation or evisceration in patients with infectious endophthalmitis. A retrospective chart review of subjects with a clinical diagnosis of infectious endophthalmitis was undertaken. The affected eyes were stratified into groups: those that underwent ENEV and those in which the eyeball was preserved (EP). The groups were compared using statistical analyses. In total, 69 eyes diagnosed with infectious endophthalmitis were included in the study. There was a higher frequency of exogenous infectious endophthalmitis in the ENEV group versus the EP group. Postsurgical infectious endophthalmitis was lower in the ENEV than in the EP group. A visual acuity of no light perception was more common in the ENEV compared to the EP group. Panophthalmitis was more frequent in the ENEV versus the EP group. Our findings suggest that eyes with endophthalmitis presenting with a visual acuity of no light perception, panophthalmitis, or exogenous etiology have a higher risk of requiring ENEV. In addition, eyes with a postsurgical etiology may be at a lower risk of requiring ENEV.
眼内炎的治疗包括玻璃体内注射抗生素，在某些情况下还包括玻璃体切割术。然而，严重或难治性病例可能需要眼球摘除术或眼内容剜出术（ENEV）。我们的研究旨在确定感染性眼内炎患者发生眼球摘除术或眼内容剜出术的危险因素。对临床诊断为感染性眼内炎的患者进行了回顾性病历审查。将受影响的眼睛分为两组：接受ENEV的眼睛和眼球得以保留（EP）的眼睛。使用统计分析对两组进行比较。该研究共纳入69只诊断为感染性眼内炎的眼睛。与EP组相比，ENEV组中外源性感染性眼内炎的发生率更高。ENEV组中术后感染性眼内炎的发生率低于EP组。与EP组相比，ENEV组中无光感视力更为常见。与EP组相比，ENEV组中全眼球炎更为频繁。我们的研究结果表明，视力无光感、全眼球炎或外源性病因的眼内炎患者需要进行ENEV的风险更高。此外，术后病因的眼睛需要进行ENEV的风险可能较低。
